肺磁共振成像与胸部断层扫描在系统性硬化症患者中检测炎症类似

Carolina de Souza Müller , Danny Warszawiak , Eduardo dos Santos Paiva , Dante Luiz Escuissato
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引用次数: 3

摘要

间质性肺病(ILD)和肺动脉高压(PAH)是系统性硬化症(SSc)的常见并发症,也是目前与该疾病相关的主要死亡原因。因此,准确识别这些情况对患者管理至关重要。一项研究对24名SSc患者和14名健康志愿者进行了随访,这些患者在联邦大学医院Clínicas (UFPR)风湿病学系接受了随访,目的是评估肺磁共振成像(MRI)在评估SS患者ILD时的有效性。将肺部MRI结果与胸部计算机断层扫描(CT)结果进行比较,后者目前被认为是SS患者ILD调查的首选检查方法。评估人群主要由平均年龄为50岁、皮肤SS有限、病程约为7年的女性组成。在大多数病例中,胸部CT和肺部MRI的表现一致。考虑到它是一种无辐射的检查,能够准确识别肺组织炎症累及的区域,肺部MRI显示是一种有用的检查,在评估SS患者的ILD活动时,使用肺部MRI是否优于胸部CT,需要进一步的研究来评估。
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Pulmonary magnetic resonance imaging is similar to chest tomography in detecting inflammation in patients with systemic sclerosis

Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) are prevalent complications of systemic sclerosis (SSc) and are currently the leading causes of death related to the disease. The accurate recognition of these conditions is therefore of utmost importance for patient management.

A study was carried out with 24 SSc patients being followed at the Rheumatology Department of the Hospital de Clínicas of Universidade Federal do Paraná (UFPR) and 14 healthy volunteers, with the objective of evaluating the usefulness of lung magnetic resonance imaging (MRI) when assessing ILD in SS patients. The results obtained with lung MRI were compared to those obtained by computed tomography (CT) of the chest, currently considered the examination of choice when investigating ILD in SS patients.

The assessed population was predominantly composed of women with a mean age of 50 years, limited cutaneous SS, and a disease duration of approximately 7 years. In most cases, there was agreement between the findings on chest CT and lung MRI. Considering it is a radiation-free examination and capable of accurately identifying areas of lung tissue inflammatory involvement, lung MRI showed to be a useful examination, and further studies are needed to assess whether there is an advantage in using lung MRI instead of chest CT when assessing ILD activity in SS patients.

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