模拟波特病的前列腺癌脊柱骨转移的不典型表现。

Q3 Medicine Clinical Cases in Mineral and Bone Metabolism Pub Date : 2017-05-01 Epub Date: 2017-10-25 DOI:10.11138/ccmbm/2017.14.1.239
Jérémy Flais, Guillaume Coiffier, Eric Brillet, Aleth Perdriger, Pascal Guggenbuhl
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引用次数: 5

摘要

55岁男性因腰痛3个月住院。脊柱MRI显示提示L5-S1-S2多节段椎间盘炎伴椎旁脓肿。胸腹CT扫描证实多处病理淋巴结,双侧肺小结节浸润;同时显示椎体L5和S1终板镜像骨侵蚀,提示弥散性结核伴肺受累和淋巴结病变。发现性L5-S1活检证实了转移性前列腺腺癌的诊断,包括椎间盘的肿瘤浸润,没有争论脓毒性进程合并结核性肉芽肿。虽然罕见,但在椎间盘-椎体交界处转移的病例,包括前列腺癌,已经被描述过,临床医生应该知道。在某些情况下,在椎间盘周围,在硬膜外炎和软组织受累的情况下,传染性脊柱炎的鉴别诊断在MRI序列上是困难的。椎间盘活检仍然是诊断的基础。
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Atypical presentation of spine bone metastasis in prostate cancer mimicking Pott's disease.

A 55-year-old man was hospitalized for a low back pain lasting for 3 months. Spinal MRI revealed a suggestive aspect of multilevel discitis L5-S1-S2 with paravertebral abscess. A thoraco-abdominal CT scan confirmed the presence of multiple pathological lymph nodes in several locations, bilateral micronodular pulmonary infiltrate; it also showed mirror bone erosions of vertebral L5 and S1 endplates, suggestive of disseminated tuberculosis with lung involvement and lymphadenopathy. A discovertebral L5-S1 biopsy was performed confirming the diagnosis of metastatic prostatic adenocarcinoma including a tumor infiltration of the intervertebral disc, without arguments for a septic processus superimposed without tuberculosis granuloma. Although rare, cases of metastases located at the disco-vertebral junction including prostatic cancer have already been described, and should be known to the clinician. The differential diagnosis with an infectious spondylodiscitis can be difficult in some case around the vertebral disc and in case of epiduritis and soft tissues involvement on MRI sequences. Disco-vertebral biopsy remains the cornerstone of the diagnosis.

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来源期刊
Clinical Cases in Mineral and Bone Metabolism
Clinical Cases in Mineral and Bone Metabolism ENDOCRINOLOGY & METABOLISM-
CiteScore
2.60
自引率
0.00%
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0
期刊介绍: The Journal encourages the submission of case reports and clinical vignettes that provide new and exciting insights into the pathophysiology and characteristics of disorders related to skeletal function and mineral metabolism and/or highlight pratical diagnostic and /or therapeutic considerations.
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