Huba Kalász, Julianna Thuróczy, Gellért Karvaly, Lajos Balogh, István Gyertyán, Edit Tóth-Molnár, Ernest Adeghate, Kornélia Tekes
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Effects on Sperms' Quality of Selegiline in Aged Rats.
Background: Selegiline is used to treat Parkinsonian patients. Other indications of its use have recently been discovered.
Objective: Scouting special and beneficial side effects of selegiline treatment.
Method: Two-year old male Wistar rats were daily treated with 0.25 mg/kg of selegiline s.c. (subcutaneous injection). The rats were sacrificed following a four-weeks' treatment.
Results: Mass of testes, number of sperms, progressive motility of sperms, and their viability definitely increased.
Conclusion: Selegiline can successfully be used to stop/counterbalance certain symptoms of aging.
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