壳聚糖及其衍生物与细胞相互作用的机制。

A A Zubareva, E V Svirshchevskaya
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引用次数: 0

摘要

本文综述了壳聚糖等分子与哺乳动物细胞相互作用的机理以及基于这些分子的给药系统的研究进展。不同物理化学性质的壳聚糖和纳米颗粒在细胞内的结合、内吞作用和进一步分布机制目前尚不清楚。
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[Mechanisms of the interaction of chitosan and its derivatives with the cell].

The review summarizes the data on the mechanisms of the interaction of chitosan and other molecules, as well as the drug delivery systems based on them, with mammalian cells. The mechanisms of binding, endocytosis, and the further distribution of chitosan and nanoparticles with different physic-chemical properties in cells remain unclear at the present time.

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