[从健康人及不同病理患者分离的肠球菌的抗生素耐药性]

Q4 Medicine Antibiotiki i Khimioterapiya Pub Date : 2016-01-01
M V Sycheva, O L Kartashova, N E Shchepitova, Al A Safronov
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引用次数: 0

摘要

观察到肠球菌对目前使用的抗生素,如四环素、环丙沙星和氨苄西林具有高耐药性。链霉素、庆大霉素和万古霉素对肠球菌临床分离株的抑菌活性最高,链霉素和庆大霉素对肠球菌的抑菌活性最高。PCR结果显示菌株对氨基糖苷类、糖肽类和四环素耐药的遗传决定因素存在。通过细菌学和遗传学检测结果的比较,发现粪便和临床分离的肠球菌具有对氨基糖苷类和糖肽类的耐药基因,但仍未对上述抗菌药物产生明显的临床耐药。
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[Antibiotic Resistance of Enterococci Isolated from Healthy Humans and Patients with Various Pathologies.]

High resistance of enterococci to the currently used antibacterials, such as tetracycline, ciprofloxacin and ampicillin was observed. Streptomycin, gentamicin and vancomycin showed the highest activity against the clinical isolates of Enterococcus spp. Streptomycin and gentamicin showed the highest activity against the intestinal enterococci. The PCR revealed the presence of the genetic determinants of resistance to aminoglycosides, glycopeptides and tetracycline in the isolates. The comparison of the results of the bacteriological and genetic tests provided detection of fecal and clinical isolates of Enterococcus spp. possessing the genes of resistance to aminoglycosides and glycopeptides, still without the finally developed significant clinical resistance to the above antibacterials.

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来源期刊
Antibiotiki i Khimioterapiya
Antibiotiki i Khimioterapiya Medicine-Infectious Diseases
CiteScore
0.80
自引率
0.00%
发文量
46
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