{"title":"甲基叔丁基醚降解分枝杆菌ENV421株丙烷代谢的基因组分析","authors":"Peter Robert Tupa, Hisako Masuda","doi":"10.7150/jgen.24929","DOIUrl":null,"url":null,"abstract":"<p><p>Methyl <i>tert</i>-butyl ether (MTBE) is a ground water contaminant with plausible carcinogenic properties. <i>Mycobacterium</i> sp. strain ENV421 cometabolically degrades MTBE and other ethers during the growth on propane as a carbon source. In this study, the 6.2 Mb genome of strain ENV421 was deciphered. The genome sequence revealed the presence of numerous putative propane catabolic genes including genes encoding hydrocarbon oxygenases and short chain alcohol dehydrogenases. These data provide the basis for the elucidation of propane metabolic pathways in strain ENV421 and its application for the remediation of ground water contaminated with toxic ethers.</p>","PeriodicalId":15834,"journal":{"name":"Journal of Genomics","volume":"6 ","pages":"24-29"},"PeriodicalIF":0.0000,"publicationDate":"2018-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.7150/jgen.24929","citationCount":"7","resultStr":"{\"title\":\"Genomic Analysis of Propane Metabolism in Methyl <i>Tert</i>-Butyl Ether-Degrading <i>Mycobacterium</i> Sp. Strain ENV421.\",\"authors\":\"Peter Robert Tupa, Hisako Masuda\",\"doi\":\"10.7150/jgen.24929\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Methyl <i>tert</i>-butyl ether (MTBE) is a ground water contaminant with plausible carcinogenic properties. <i>Mycobacterium</i> sp. strain ENV421 cometabolically degrades MTBE and other ethers during the growth on propane as a carbon source. In this study, the 6.2 Mb genome of strain ENV421 was deciphered. The genome sequence revealed the presence of numerous putative propane catabolic genes including genes encoding hydrocarbon oxygenases and short chain alcohol dehydrogenases. These data provide the basis for the elucidation of propane metabolic pathways in strain ENV421 and its application for the remediation of ground water contaminated with toxic ethers.</p>\",\"PeriodicalId\":15834,\"journal\":{\"name\":\"Journal of Genomics\",\"volume\":\"6 \",\"pages\":\"24-29\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-03-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.7150/jgen.24929\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Genomics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7150/jgen.24929\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2018/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Genomics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7150/jgen.24929","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2018/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Genomic Analysis of Propane Metabolism in Methyl Tert-Butyl Ether-Degrading Mycobacterium Sp. Strain ENV421.
Methyl tert-butyl ether (MTBE) is a ground water contaminant with plausible carcinogenic properties. Mycobacterium sp. strain ENV421 cometabolically degrades MTBE and other ethers during the growth on propane as a carbon source. In this study, the 6.2 Mb genome of strain ENV421 was deciphered. The genome sequence revealed the presence of numerous putative propane catabolic genes including genes encoding hydrocarbon oxygenases and short chain alcohol dehydrogenases. These data provide the basis for the elucidation of propane metabolic pathways in strain ENV421 and its application for the remediation of ground water contaminated with toxic ethers.
期刊介绍：
Journal of Genomics publishes papers of high quality in all areas of gene, genetics, genomics, proteomics, metabolomics, DNA/RNA, computational biology, bioinformatics, and other relevant areas of research and application. Articles published by the journal are rigorously peer-reviewed. Types of articles include: Research paper, Short research communication, Review or mini-reviews, Commentary, Database, Software.
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