OC-2-KB:一个建立基于证据的肥胖和癌症知识库的软件管道。

Juan Antonio Lossio-Ventura, William Hogan, François Modave, Yi Guo, Zhe He, Amanda Hicks, Jiang Bian
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摘要

肥胖与几种癌症有关。获得适当的卫生信息可促使人们参与管理自己的健康,从而最终改善他们的健康结果。然而,现有的关于肥胖和癌症之间关系的在线信息是异构的,而且组织不健全。正式的知识表示可以帮助更好地组织和提供高质量的健康信息。目前,在生物医学领域有一些将非结构化数据转换为结构化数据并存储在语义Web知识库中的研究。在这篇演示论文中,我们介绍了OC-2-KB (Obesity and Cancer to Knowledge Base),这是一个专门用于指导自动知识库构建的系统,用于系统地管理自由文本科学文献(即PubMed摘要)中的肥胖和癌症知识。OC-2-KB有两个重要的模块,分别用于实体的获取和实体之间关系的提取和分类。我们在一个包含23篇人工标注的肥胖和癌症PubMed摘要的数据集上测试了OC-2-KB系统,并创建了一个包含765个三元组的初步KB。我们对该样本进行了初步评估,并报告了我们的评估结果。
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OC-2-KB: A software pipeline to build an evidence-based obesity and cancer knowledge base.

Obesity has been linked to several types of cancer. Access to adequate health information activates people's participation in managing their own health, which ultimately improves their health outcomes. Nevertheless, the existing online information about the relationship between obesity and cancer is heterogeneous and poorly organized. A formal knowledge representation can help better organize and deliver quality health information. Currently, there are several efforts in the biomedical domain to convert unstructured data to structured data and store them in Semantic Web knowledge bases (KB). In this demo paper, we present, OC-2-KB (Obesity and Cancer to Knowledge Base), a system that is tailored to guide the automatic KB construction for managing obesity and cancer knowledge from free-text scientific literature (i.e., PubMed abstracts) in a systematic way. OC-2-KB has two important modules which perform the acquisition of entities and the extraction then classification of relationships among these entities. We tested the OC-2-KB system on a data set with 23 manually annotated obesity and cancer PubMed abstracts and created a preliminary KB with 765 triples. We conducted a preliminary evaluation on this sample of triples and reported our evaluation results.

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