[硫化氢在继发性肾脏疾病和肾移植中的保护作用]。

生理科学进展 Pub Date : 2016-04-01

Yan-Ting Yu, Jun-Wei Yang

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引用次数: 0

摘要

肾脏疾病的发病率不断上升，已成为威胁人民健康的重要因素。硫化氢是继CO和NO之后的第三种气体信号分子。高浓度时具有毒性作用，但在生理浓度时具有舒张血管、抗氧化、抗炎症、抗细胞凋亡等重要作用。肾脏疾病，特别是继发性肾脏疾病，如阻塞性肾病、肾移植、糖尿病肾病、高血压肾病等，与血管病变、氧化应激和炎症密切相关。那么硫化氢和肾病之间有什么关系呢?本文将综述硫化氢与肾脏疾病的关系。

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[Protective Effect of Hydrogen Sulfide in the Secondary Renal Disease and Renal Transplantation].

The prevalence of kidney disease was increasing,which has become an important threaten to the health of the population.Hydrogen sulfide is the third gas signaling molecules after CO and NO.It has toxic effect at high concentration,but plays an important role in relaxing blood vessel ,antioxidation anti -inflammation and anti-apoptosis at physiological concentration.Kidney disease,especially seconda-ry kidney disease such as obstructive nephropathy,renal transplantation,diabetic nephropathy and hyper-tensive kidney lesion are closely related to vascular leision,oxidative stress and inflammation.Then what's the relationship between hydrogen sulfide and kidney disease?This article will review the relationship between hydrogen sulfide and kidney disease.

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来源期刊

生理科学进展

自引率

0.00%

发文量

5953

期刊介绍： Progress in Physiological Sciences is a bimonthly academic journal co-sponsored by Chinese Association for Science and Technology, Chinese Physiological Society and Peking University. It was founded in March 1957. China Core Journal of Science and Technology, China Core Journal of Medicine and Health, Statistical source journal of Chinese Academic Journal Impact Factor Annual Report, China Science Citation Database CSCD (1996-2018); Overview of Key Chinese Core Journals of Peking University (1992-2020, 2023-), It has been reported by China Journal Network, China Academic Journals (Optical Disc Edition), China Biomedical Citation Database CMCI, Science and Technology Journals World Impact Index (WJCI) (2022), Wanfang Data Resource System digital Journal Group (China Core Journal Database); American Medical Index (IM), American Chemical Abstracts (CA), etc. Progress in Physiological Sciences is published at home and abroad. The journal comprehensively reports the new progress in physiological sciences at home and abroad, and publishes review papers related to physiological sciences, namely physiology, biochemistry and molecular biology, pharmacology, pathophysiology, biophysics, nutrition, etc.