{"title":"Cryptolepis sanguinolenta (Lindl.) Schlechter 的植物化学和药理综述。","authors":"Newman Osafo, Kwesi Boadu Mensah, Oduro Kofi Yeboah","doi":"10.1155/2017/3026370","DOIUrl":null,"url":null,"abstract":"<p><strong>Ethnopharmacological relevance: </strong><i>Cryptolepis sanguinolenta</i> is a scrambling thin-stemmed shrub found in Africa. Traditionally in West Africa, it is employed in the treatment of malaria, diarrhea, and respiratory conditions. This review discusses the traditional importance as well as the phytochemical, ethnomedical, pharmacological, and toxicological importance of this plant.</p><p><strong>Materials and methods: </strong>Excerpta Medica Database, Google Scholar, Springer, and PubMed Central were the electronic databases used to search for and filter primary studies on <i>Cryptolepis sanguinolenta</i>.</p><p><strong>Results: </strong>The detailed review of various studies conducted on <i>C. sanguinolenta</i> and some of its constituents gives an important body of proof of its potential therapeutic benefits and also of its use as a source of lead compounds with therapeutic potentials.</p><p><strong>Conclusion: </strong>The review on <i>C. sanguinolenta</i> is important in identifying grey areas in the research on this medicinal plant and also provides comprehensive data thus far to continue research on this plant.</p>","PeriodicalId":7389,"journal":{"name":"Advances in Pharmacological Sciences","volume":"2017 ","pages":"3026370"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661077/pdf/","citationCount":"0","resultStr":"{\"title\":\"Phytochemical and Pharmacological Review of <i>Cryptolepis sanguinolenta</i> (Lindl.) Schlechter.\",\"authors\":\"Newman Osafo, Kwesi Boadu Mensah, Oduro Kofi Yeboah\",\"doi\":\"10.1155/2017/3026370\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Ethnopharmacological relevance: </strong><i>Cryptolepis sanguinolenta</i> is a scrambling thin-stemmed shrub found in Africa. Traditionally in West Africa, it is employed in the treatment of malaria, diarrhea, and respiratory conditions. This review discusses the traditional importance as well as the phytochemical, ethnomedical, pharmacological, and toxicological importance of this plant.</p><p><strong>Materials and methods: </strong>Excerpta Medica Database, Google Scholar, Springer, and PubMed Central were the electronic databases used to search for and filter primary studies on <i>Cryptolepis sanguinolenta</i>.</p><p><strong>Results: </strong>The detailed review of various studies conducted on <i>C. sanguinolenta</i> and some of its constituents gives an important body of proof of its potential therapeutic benefits and also of its use as a source of lead compounds with therapeutic potentials.</p><p><strong>Conclusion: </strong>The review on <i>C. sanguinolenta</i> is important in identifying grey areas in the research on this medicinal plant and also provides comprehensive data thus far to continue research on this plant.</p>\",\"PeriodicalId\":7389,\"journal\":{\"name\":\"Advances in Pharmacological Sciences\",\"volume\":\"2017 \",\"pages\":\"3026370\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661077/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Pharmacological Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2017/3026370\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2017/10/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Pharmacological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2017/3026370","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/10/15 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 0
摘要
民族药理学意义:Cryptolepis sanguinolenta 是一种生长在非洲的蔓生细茎灌木。在西非的传统中,它被用于治疗疟疾、腹泻和呼吸道疾病。这篇综述讨论了这种植物的传统重要性以及植物化学、民族医学、药理学和毒理学方面的重要性:Excerpta Medica Database、Google Scholar、Springer 和 PubMed Central 是用于搜索和筛选 Cryptolepis sanguinolenta 主要研究的电子数据库:结果:对 C. sanguinolenta 及其部分成分进行的各种研究的详细综述为其潜在的治疗功效提供了重要的证据,也为其作为具有治疗潜力的先导化合物的来源提供了重要的证据:关于 C. sanguinolenta 的综述对于确定这种药用植物研究中的灰色地带非常重要,同时也为继续研究这种植物提供了全面的数据。
Phytochemical and Pharmacological Review of Cryptolepis sanguinolenta (Lindl.) Schlechter.
Ethnopharmacological relevance: Cryptolepis sanguinolenta is a scrambling thin-stemmed shrub found in Africa. Traditionally in West Africa, it is employed in the treatment of malaria, diarrhea, and respiratory conditions. This review discusses the traditional importance as well as the phytochemical, ethnomedical, pharmacological, and toxicological importance of this plant.
Materials and methods: Excerpta Medica Database, Google Scholar, Springer, and PubMed Central were the electronic databases used to search for and filter primary studies on Cryptolepis sanguinolenta.
Results: The detailed review of various studies conducted on C. sanguinolenta and some of its constituents gives an important body of proof of its potential therapeutic benefits and also of its use as a source of lead compounds with therapeutic potentials.
Conclusion: The review on C. sanguinolenta is important in identifying grey areas in the research on this medicinal plant and also provides comprehensive data thus far to continue research on this plant.
期刊介绍:
Advances in Pharmacological and Pharmaceutical Sciences is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of experimental and clinical pharmacology, pharmaceutics, medicinal chemistry and drug delivery. Topics covered by the journal include, but are not limited to: -Biochemical pharmacology, drug mechanism of action, pharmacodynamics, pharmacogenetics, pharmacokinetics, and toxicology. -The design and preparation of new drugs, and their safety and efficacy in humans, including descriptions of drug dosage forms. -All areas of medicinal chemistry, such as drug discovery, design and synthesis. -Basic biology of drug and gene delivery through to application and development of these principles, through therapeutic delivery and targeting. Areas covered include bioavailability, controlled release, microcapsules, novel drug delivery systems, personalized drug delivery, and techniques for passing biological barriers.