THE INCIDENCE OF COLORECTAL CANCER IN KAZAKHSTAN.

The purpose of the study is to examine the situation and to ascertain the features of incidence and mortality of colorectal cancer (CRC) in Kazakhstan in 2004-2013 and to give a forecast until 2020.

Materials and methods: The data of new cases and deaths, which are available in the Cancer Registry of Research Institute of Oncology and Radiology of the Republic of Kazakhstan, were applied. in the analyzes the modern methods of variation statistics were applied to determine the average relative number, the study of time series, standard errors of means and other indicators.

Results: The average 10-year CRR incidence was 15.5?0.31 cases per 100 000 population, and the rate of increase reached 2.04% per year where higher rates (+2.28%) were typical for colon cancer. Age is one of the most important factors in the development of CRC. In 30-39 years, the incidence rate increased 11.5 times relative to the age grouping up to 30 years, in 50-59 and 60-69 years, the incidence increases 3.2 and 2.5 times respectively, relative to the previous level. In the group older than 70 years the incidence is 121.1?4.04. On the average during the study period the CRR incidence among females is 1.2 times higher than among males.

Conclusion: The high correlation of developing CRC by age and sex was determined. The death rate from CRC was 9.6?0.25 cases per 100 000. According to the forecast for 2020 the CRC incidence will increase by 11%, and the mortality will not significantly change.