啮齿类动物静息状态功能磁共振成像

Q2 Neuroscience Current Protocols in Neuroscience Pub Date : 2018-04-26 DOI:10.1002/cpns.45
Wen-Ju Pan, Jacob Billings, Maysam Nezafati, Anzar Abbas, Shella Keilholz
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引用次数: 4

摘要

静息状态功能磁共振成像(fMRI)和功能连接被广泛应用于人类,以研究大脑网络在正常功能和功能障碍中的作用。在啮齿类动物身上也可以采用类似的方法,要么在大脑疾病模型中获得翻译测量,要么更仔细地检查网络的神经生理学基础。描述了麻醉大鼠静息状态功能连接的协议,从动物设置到数据采集到可能的数据分析管道。©2018 by John Wiley &儿子,Inc。
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Resting State fMRI in Rodents

Resting state functional MRI (fMRI) and functional connectivity are widely applied in humans to examine the role of brain networks in normal function and dysfunction. A similar approach can be taken in rodents, either to obtain translational measures in models of brain disorders or to more carefully examine the neurophysiological underpinnings of the networks. A protocol for resting state functional connectivity in the anesthetized rat, from animal setup to data acquisition to possible pipelines for data analysis, is described. © 2018 by John Wiley & Sons, Inc.

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Current Protocols in Neuroscience
Current Protocols in Neuroscience Neuroscience-Neuroscience (all)
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期刊介绍: Current Protocols in Neuroscience is a one-stop resource for finding and adapting the best models and methods for all types of neuroscience experiments. Updated every three months in all formats, CPNS is constantly evolving to keep pace with the very latest discoveries and developments. A year of these quarterly updates is included in the initial CPNS purchase price.
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