连续监测设备和癫痫发作模式的葡萄糖，时间和侧化癫痫发作

Epilepsy and Behavior Case Reports Pub Date : 2018-01-01 DOI:10.1016/j.ebcr.2018.03.001

Katie M. Kinnear, Nicole M. Warner, Alan M. Haltiner, Michael J. Doherty

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引用次数: 4

摘要

目的探讨血糖水平对癫痫发作模式的影响。材料与方法1例双颞部植入RNS/NeuroPace的1型糖尿病患者，癫痫发作次数和发作部位与连续组织葡萄糖相匹配。结果左局灶性发作(LFS, n = 22)平均血糖为169 mg/dL，右局灶性发作(RFS, n = 23)平均血糖为131 mg/dL (p = 0.03)。LFS发生在平均时间17:02,RFS发生在平均时间04:23。LFS向对侧扩散(n = 19)多于RFS (n = 2)。结论癫痫发作的侧边性和扩散随血糖和发作时间的不同而不同。

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Continuous monitoring devices and seizure patterns by glucose, time and lateralized seizure onset

Objectives

To investigate if glucose levels influence seizure patterns.

Materials and methods

In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose.

Results

Left focal seizure (LFS, n = 22) glucoses averaged 169 mg/dL, while right focal seizure (RFS, n = 23) glucoses averaged 131 mg/dL (p = 0.03). LFS occurred at mean time 17:02 while RFS occurred at 04:23. LFS spread to the contralateral side (n = 19) more than RFS (n = 2).

Conclusion

Seizure onset laterality and spread vary with glucose and time of seizure.

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Epilepsy and Behavior Case Reports

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