【高效液相色谱法分析云南民间医药常用青叶丹环烯醚萜苷】。

中药材 Pub Date : 2016-06-01
Hai-lan Fang, Fei-neng Shang, Xian-ying Yang, Cong-long Xia, Bao-zhong Duan
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引用次数: 0

摘要

目的:比较清叶丹药材中环烯醚萜苷类成分的含量,为清叶丹资源的合理利用和原植物药的合理性提供科学依据。方法:采用高效液相色谱法测定清叶丹药材中獐牙菜苦苷、龙胆苦苷和獐牙菜苦苷三种环烯醚萜苷类成分的含量。结果:9种药材中30个样品的成分差异有统计学意义。同时首次报道了獐牙菜、獐牙菜和獐牙菜中环烯醚萜苷的含量。结论:青叶丹药材中环烯醚萜苷的含量因品种和产地的不同而存在显著差异。因此,这些药用植物不应作为替代药物用于临床应用。选取獐牙菜苦苷和獐牙菜苷作为质量控制成分,该方法是鉴别和控制清叶丹药材质量的有效方法。
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[HPLC Analyzed the Iridoid Glycosides of Qingyedan Commonly Used in Folk Medicine in Yunnan].

Objective: To compare the contents of iridoid glycosides in Qingyedan medicinal materials,and to provide the scientific basis for using resources of Qingyedan and rationality of original plant medicinal.

Methods: The contens of three iridoid glycosides,including swertiamarin,gentiopicroside and sweroside in Qingyedan medicinal materials were determined by HPLC.

Results: The constituents of 30 samples in nine species were significant difference. And the contents of iridoid glycosides in Swertia bimaculata,Swertia tenuis and Swertia pubescens were reported for the first time.

Conclusion: The results show that the contents of iridoid glycosides in Qingyedan medicinal materials have a significant difference due to the different species and producing areas. Therefore, these medicinal plants should not be used as alternative medicines for clinical application. Swertiamarin and sweroside can be selected as quality control components, this method is an effective method to identify and control the quality of Qingyedan materials.

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期刊介绍: "Chinese Materia Medica" magazine was founded in 1978. It is a national-level academic journal of Chinese medicine science and technology approved by the State Science and Technology Commission and the Press and Publication Administration for public distribution at home and abroad. It is sponsored by the Chinese Materia Medica Information Center of the State Food and Drug Administration and is publicly distributed at home and abroad. It mainly reports on new technologies, new methods and new achievements in the production, scientific research and business management of Chinese medicine, and serves to promote the production and scientific and technological development of Chinese medicine, improve the output and quality of Chinese medicine, improve business management, and prosper the Chinese medicine industry.
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