Regorafenib和resce试验:肝细胞癌患者的新二线选择

IF 1.2 Q4 ONCOLOGY Hepatic Oncology Pub Date : 2016-08-01 Epub Date: 2016-08-19 DOI:10.2217/hep-2016-0007
Jordi Bruix
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引用次数: 1

摘要

Jordi Bruix博士*与编辑主任Laura Dormer交谈:Jordi Bruix博士是西班牙巴塞罗那大学医院诊所巴塞罗那诊所肝癌(BCLC)小组的负责人,也是西班牙研究所肝脏和消化系统疾病研究网络(CIBEREHD)的主任。他的研究改变了肝癌的诊断和治疗。主要亮点包括:BCLC分期和治疗的发展;肝细胞癌诊断标准的发展门静脉压力在预测切除后预后中的价值并担任III期试验的首席研究员,该试验显示化疗栓塞、索拉非尼和瑞非尼对肝癌患者的益处。他撰写了欧洲肝脏研究协会,美国肝脏疾病研究协会和世界胃肠病组织实践指南以及器官共享肝细胞癌(HCC)诊断标准联合网络。
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Regorafenib and the RESORCE trial: a new second-line option for hepatocellular carcinoma patients.

Dr Jordi Bruix* speaks to Laura Dormer, Editorial Director: Dr Jordi Bruix is the Head of the Barcelona Clinic Liver Cancer (BCLC) group at the Hospital Clinic (University of Barcelona, Spain) and Director of the Network for Research in Liver and Digestive Disease (CIBEREHD) in the Spanish Research Institute. His research has changed the diagnosis and treatment of liver cancer. Major highlights include: development of the BCLC staging and treatment; development of diagnostic criteria for hepatocellular carcinoma; identification of the value of portal pressure in predicting prognosis after resection; and acting as principal investigator of the Phase III trials that have shown the benefits of chemoembolization, sorafenib and regorafenib for patients with liver cancer. He has authored the European Assoaciation for the Study of the Liver, American Association for the Study of Liver Diseases and World Gastroenterology Organization Practice Guidelines and the United Network for Organ Sharing hepatocellular carcinoma (HCC) diagnostic criteria.

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来源期刊
Hepatic Oncology
Hepatic Oncology ONCOLOGY-
CiteScore
0.40
自引率
0.00%
发文量
4
审稿时长
13 weeks
期刊介绍: Primary liver cancer is the sixth most common cancer in the world, and the third most common cause of death from malignant disease. Traditionally more common in developing countries, hepatocellular carcinoma is becoming increasingly prevalent in the Western world, primarily due to an increase in hepatitis C virus infection. Emerging risk factors, such as non-alcoholic fatty liver disease and obesity are also of concern for the future. In addition, metastatic tumors of the liver are more common than primary disease. Some studies report hepatic metastases in as many as 40 to 50% of adult patients with extrahepatic primary tumors. Hepatic Oncology publishes original research studies and reviews addressing preventive, diagnostic and therapeutic approaches to all types of cancer of the liver, in both the adult and pediatric populations. The journal also highlights significant advances in basic and translational research, and places them in context for future therapy. Hepatic Oncology provides a forum to report and debate all aspects of cancer of the liver and bile ducts. The journal publishes original research studies, full reviews and commentaries, with all articles subject to independent review by a minimum of three independent experts. Unsolicited article proposals are welcomed and authors are required to comply fully with the journal''s Disclosure & Conflict of Interest Policy as well as major publishing guidelines, including ICMJE and GPP3.
期刊最新文献
APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage. Comparison of long-term clinical outcomes between radiofrequency ablation and hepatic resection in patients with small (≤2 cm) hepatocellular carcinoma. Integration of circulating tumor DNA in biliary tract cancer: the emerging landscape. Role of immunotherapy in the overall survival of gastrointestinal cancer patients with liver metastases. Treatment journey of patients with hepatocellular carcinoma using real-world data in British Columbia, Canada.
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