自发性部分感觉剥夺对雄性c57bl / 6n小鼠行为的影响

M A Tur, I V Belozertseva
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引用次数: 0

摘要

与群体内社会互动特性相关的触须缺失可能是影响动物在各种行为测试中的表现的重要因素。为了评估由于笼中同伴的理发活动而引起的自发性部分感觉剥夺的影响,在雄性C57Bl/6N小鼠中进行了一系列试验。结果表明,无触须小鼠在试管、野外、社会交往和强迫游泳试验中的行为与对照组有显著差异。因此,目前的研究结果表明,在将动物纳入实验组和/或在数据分析中进一步考虑之前,必须评估触须状况。
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[NFLUENCE OF SPONTANEOUS PARTIAL SENSORY DEPRIVATION ON MALE C57BL/6N MICE BEHAVIOR].

Vibrissae loss associated with the peculiarities of the intragroup social interaction may be an important factor affecting the animals’ performance in various behavioral tests. To evaluate the influence of spontaneous partial sensory deprivation as a consequence of the barbering activity of a cage mate, the battery of tests was conducted in male C57Bl/6N mice. The results indicate that the behavior of mice without vibrissae significantly differs from control animals in the tube, open field, social interaction and forced swim tests. Thus, the present findings suggest that vibrissae conditions have to be assessed before the inclusion of animals into experimental groups and/or further considered in data analysis.

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