A V Chajka, D R Khusainov, I V Cheretaev, I I Koreniuk, A D Nozdracev
{"title":"慢性d2受体阻断对低抑郁大鼠行为的影响。","authors":"A V Chajka, D R Khusainov, I V Cheretaev, I I Koreniuk, A D Nozdracev","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The article is devoted to investigation of influence of chronic D2-receptor blockade by haloperidol on behavior low depressive rats. It is shown that chronic D2-receptor blockade by haloperidol (2.5 mg/kg) causes pro-depressant effect on behavior of low depressive rats and leads to the formation of the depressed state. In control and experimental groups, identified circaseptan and circasemiseptan rhythms in the dynamics of the index of depression, characterized by a phase shift relative to each other.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"172-81"},"PeriodicalIF":0.0000,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[CHRONIC D2-RECEPTOR BLOCKADE AND BEHAVIOR OF LOW DEPRESSIVE RATS].\",\"authors\":\"A V Chajka, D R Khusainov, I V Cheretaev, I I Koreniuk, A D Nozdracev\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The article is devoted to investigation of influence of chronic D2-receptor blockade by haloperidol on behavior low depressive rats. It is shown that chronic D2-receptor blockade by haloperidol (2.5 mg/kg) causes pro-depressant effect on behavior of low depressive rats and leads to the formation of the depressed state. In control and experimental groups, identified circaseptan and circasemiseptan rhythms in the dynamics of the index of depression, characterized by a phase shift relative to each other.</p>\",\"PeriodicalId\":21358,\"journal\":{\"name\":\"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova\",\"volume\":\"103 2\",\"pages\":\"172-81\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[CHRONIC D2-RECEPTOR BLOCKADE AND BEHAVIOR OF LOW DEPRESSIVE RATS].
The article is devoted to investigation of influence of chronic D2-receptor blockade by haloperidol on behavior low depressive rats. It is shown that chronic D2-receptor blockade by haloperidol (2.5 mg/kg) causes pro-depressant effect on behavior of low depressive rats and leads to the formation of the depressed state. In control and experimental groups, identified circaseptan and circasemiseptan rhythms in the dynamics of the index of depression, characterized by a phase shift relative to each other.