慢性d2受体阻断对低抑郁大鼠行为的影响。

A V Chajka, D R Khusainov, I V Cheretaev, I I Koreniuk, A D Nozdracev
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引用次数: 0

摘要

本文研究氟哌啶醇慢性d2受体阻断对行为低抑郁大鼠的影响。结果表明,慢性氟哌啶醇阻断d2受体(2.5 mg/kg)对低抑郁大鼠的行为具有促抑郁作用,导致抑郁状态的形成。在对照组和实验组中,确定了circaseptan和circasemiseptan节律在抑郁指数的动态变化中,其特征是相对于彼此的相移。
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[CHRONIC D2-RECEPTOR BLOCKADE AND BEHAVIOR OF LOW DEPRESSIVE RATS].

The article is devoted to investigation of influence of chronic D2-receptor blockade by haloperidol on behavior low depressive rats. It is shown that chronic D2-receptor blockade by haloperidol (2.5 mg/kg) causes pro-depressant effect on behavior of low depressive rats and leads to the formation of the depressed state. In control and experimental groups, identified circaseptan and circasemiseptan rhythms in the dynamics of the index of depression, characterized by a phase shift relative to each other.

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