老年人晚期肝细胞癌的系统治疗。

Journal of nature and science Pub Date : 2018-08-01
Luisa M Arellano, Sukeshi Patel Arora
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摘要

在过去的 30 年中,美国的肝细胞癌(HCC)发病率增加了两倍,这主要是由于慢性丙型肝炎病毒、酒精性肝炎和非酒精性脂肪性肝炎(NASH)未经治疗所致。此外,南得克萨斯州西班牙裔的 HCC 发病率也高于美国其他地区。美国 HCC 患者的中位年龄为 62 岁,南德克萨斯州为 67 岁,其中超过 30% 的患者年龄在 70 岁或以上。然而,关于如何治疗患有晚期 HCC 的老年人的数据却很有限。在这篇综述中,我们将讨论晚期 HCC 老年人的治疗方案,进一步强调对这一人群进行前瞻性研究的必要性。
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Systemic Treatment of Advanced Hepatocellular Carcinoma in Older Adults.

Over the past 30 years, the incidence in of hepatocellular carcinoma (HCC) in the United States has tripled, largely due to untreated chronic Hepatitis C virus, alcoholic hepatitis, and non-alcoholic steatohepatitis (NASH). Additionally, the incidence of HCC among South Texas Hispanics is higher than elsewhere in the United States. The median age of HCC is 62 years in United States and 67 years in South Texas, with over 30% being 70 years of age or older. However, there is limited data on how to treat older adults with advanced HCC. In this review, we will discuss treatment options for older adults with advanced HCC, further emphasizing the need for prospective studies in this population.

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