ctx - m - 15广谱产β-内酰胺酶沙门氏菌引起的小儿急性肠炎1例。

The Japanese journal of antibiotics Pub Date : 2016-10-01
Storu Kutsuna, Shota Yonetani, Koji Araki, Hidemasa Izumiya
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引用次数: 0

摘要

本临床病例报告涉及一个小儿患者急性肠炎引起的多重耐药肠沙门氏菌血清型巴克利(巴克利沙门氏菌)。一名3岁男孩以发热、腹痛、带血腹泻5天就诊于我们的急诊室。粪便培养对沙门氏菌呈阳性,而血液培养为阴性。患者成功地接受了磷霉素口服抗生素治疗。该粪便分离株对头孢多肟、头孢噻肟、头孢他啶、氨曲南等多种药物耐药,为一株产β-内酰胺酶(ESBL)的Blockley沙门氏菌CTX-M-15菌株。这是日本首例由CTX-M-15产ESBL的沙门氏菌引起的急性肠炎的儿科患者报告。
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A case of pediatric patient with acute enteritis due to CTX-M-1 5 extended-spectrum β-lactamase-producing Salmonella Blockley.

This clinical case report concerns a pediatric patient with acute enteritis caused by multi-drug resistant Salmonella enterica serovar Blockley (Salmonella Blockley). A 3-year-old boy presented to our emergency room with a 5-day history of fever, abdominal pain, and bloody diarrhea. Stool culture tested positive for a Salmonella species, while the blood culture was negative. The patient was successfully treated with an oral antibiotic regimen of fosfomycin. The stool isolate was found to be resistant to multiple drugs, including cefpodoxime, cefotaxime, ceftazidime, and aztreonam, and was confirmed to be a CTX-M-15 extended-spectrum β-lactamase (ESBL)-producing strain of Salmonella Blockley. This is the first report of a pediatric patient in Japan with acute enteritis caused by a CTX-M-15 ESBL- producing strain of Salmonella Blockley.

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