非洲的基因组学研究及其对全球健康的影响:非洲研究人员的见解。

IF 1.1 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Global Health Epidemiology and Genomics Pub Date : 2018-06-08 eCollection Date: 2018-01-01 DOI:10.1017/gheg.2018.3
N S Munung, B M Mayosi, J de Vries
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引用次数: 0

摘要

非洲可能正迈向基因组医学时代。人们还期望基因组学能在减少全球健康不平等方面发挥作用。然而,由于几乎没有针对非洲人口的基因组学研究,人们担心基因组学可能会扩大而不是缩小全球健康不平等的差距。为了防止可能出现的基因组学鸿沟,基因组学 "革命 "已经扩展到非洲。这样做的部分原因是非洲丰富的基因多样性和沉重的疾病负担。然而,将基因组学技术用于非洲医疗保健的前景仍不明朗。在这项定性研究中,我们探讨了非洲 17 位基因组学研究人员对非洲基因组医学前景和挑战的看法。受访者均为参与非洲基因组学研究项目的非洲研究人员。对深入访谈的分析表明,基因组医学可能会对疾病监测、诊断、治疗和预防产生影响。然而,非洲的基因组医学能力、当前基因组学研究的重点以及研究成果的转化将是影响基因组医学改善非洲医疗保健能力的关键决定因素。
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Genomics research in Africa and its impact on global health: insights from African researchers.

Africa may be heading for an era of genomics medicine. There are also expectations that genomics may play a role in reducing global health inequities. However, the near lack of genomics studies on African populations has led to concerns that genomics may widen, rather than close, the global health inequity gap. To prevent a possible genomics divide, the genomics 'revolution' has been extended to Africa. This is motivated, in part, by Africa's rich genetic diversity and high disease burden. What remains unclear, however, are the prospects of using genomics technology for healthcare in Africa. In this qualitative study, we explored the views of 17 genomics researchers in Africa on the prospects and challenges of genomics medicine in Africa. Interviewees were researchers in Africa who were involved in genomics research projects in Africa. Analysis of in-depth interviews suggest that genomics medicine may have an impact on disease surveillance, diagnosis, treatment and prevention. However, Africa's capacity for genomics medicine, current research priorities in genomics and the translation of research findings will be key defining factors impacting on the ability of genomics medicine to improve healthcare in Africa.

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来源期刊
Global Health Epidemiology and Genomics
Global Health Epidemiology and Genomics PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.40
自引率
0.00%
发文量
10
审稿时长
20 weeks
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