[用长效肌松弛剂哌库溴铵输注纠正急性胰腺炎大鼠腹内压]。

Klinichna khirurgiia Pub Date : 2017-01-01

A S Morgun, A I Sukhodolya, O V Kabanov, S A Sukhodolya, M Falaleyeva, T V Beregova

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引用次数: 0

摘要

研究了肌松弛剂哌库溴铵对实验性模拟急性腹膜炎大鼠腹内压的持久作用。L- rginin诱导的化脓性胰腺炎大鼠的IAP是正常实验动物的4.5倍(p < 0.001)。哌库溴铵可使IAP降低33.4%，表明应用肌松弛剂治疗化脓性胰腺炎腹内高压有效。

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[CORRECTION OF INTRAABDOMINAL PRESSURE IN RATS IN AN ACUTE PANCREATITIS, USING INFUSION OF MYORELAXANT OF A DURABLE ACTION PIPECURONIUM BROMIDE].

Impact of a durable action of myorelaxant pipecuronium bromide on intraabdominal pressure (IAP) in rats in experimentally simulated acute peritonitis was studied. In the rats in purulent pancreatitis, іnduced by L-аrginin, IAP was in 4,5 times high (p < 0.001), than in intact laboratory animals. Pipecuronium bromide have lowered IAP by 33.4%, witnessing efficacy of application of myorelaxants in treatment of intraabdominal hypertension in purulent pancreatitis.

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Klinichna khirurgiia

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0.00%

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审稿时长

12 weeks