[在非甾体类药物胃病的问题下,成人和儿童的共病和多病]。

Y U S Serebrova, A B Prokofiev, M V Zhuravleva, I B Sichinava, E A Smolyarchuk, P L Galstyan, D O Kurguzova, N A Pankratova
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引用次数: 0

摘要

非甾体抗炎药(NSAIDs)是需求量最大的药物之一。本文综述了非甾体抗炎药在不同年龄组共病条件下的药物活性机制、有效性、安全性和主要药物相互作用,以及预防非甾体抗炎药-胃病的措施,即使使用小剂量非甾体抗炎药也可能发生胃病。关于非甾体抗炎药的选择和该药理学组药物的综合治疗的现有建议是在考虑患者的个体特征、药物的药理学特性、疾病的临床表现、不良反应和药物相互作用的危险因素的存在时显示的。
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[COMORBIDITY AND POLYMORBIDITY IN ADULTS AND CHILDREN IN THE LIGHT OF THE PROBLEM OF NSAID-GASTROPATHY].

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most demanded drugs. Paper presents the data review on the drug activity mechanisms, effectiveness, safety, and major drug interactions of NSAIDs at co-morbid conditions in different age groups, as well as measures of prevention of NSAID-gastropathy, which can occur even against the use of small doses of NSAIDs. The existing recommendations on the selection of NSAIDs and the complex therapy with drugs of this pharmacological group are shown in considering the individual characteristics of the patient, the pharmacological properties of drugs, the clinical picture of the disease, the presence of risk factors for adverse reactions and drug interactions.

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