[暴露于金属汞下中枢神经系统通路状态变化的潜在机制]。

Q4 Engineering Meditsina truda i promyshlennaia ekologiia Pub Date : 2017-01-01
D V Rusanova, O L Lakhman, G M Bodienkova, N G Kuptsova
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引用次数: 0

摘要

作者揭示了汞在代谢循环中枢机制病理改变中的作用,并与丘脑区中枢传入通路的改变有关。确定了诊断的影响强度与S-100蛋白抗体水平的变化之间的关系,一般髓鞘蛋白,髓鞘相关糖蛋白-可以指示一般神经退行性变过程。抗体水平可以作为暴露于神经毒物的中枢通路脱髓鞘强度的标志。
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[Mechanisms underlying changes in state of central nervous system pathways under exposure to metallic mercury].

The authors revealed mercury role in pathologic changes of central mechanisms underlying cerebral circulation in metabolic circle, associated with changes in central afferent pathways in thalamic region. Relationship was established between intensity of the diagnosed affect and changes in levels of antibodies to proteins S-100, general myeline protein, myeline-associated glycoprotein - that can indicate general neurodegeneration process. Antibodies level can serve as a marker of demyelination intensity in central pathways under exposure to neurotoxicants.

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来源期刊
Meditsina truda i promyshlennaia ekologiia
Meditsina truda i promyshlennaia ekologiia Medicine-Public Health, Environmental and Occupational Health
CiteScore
0.90
自引率
0.00%
发文量
80
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