【血管钙化的预防与治疗】

Kazuki Kawakami, Masaki Ohya, Takashi Shigematsu
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引用次数: 0

摘要

直到最近十年,我们一直将慢性肾脏疾病(CKD)中的各种骨骼疾病称为“ROD:肾性骨营养不良”。然而,近十年来,ROD的概念已经转变为慢性肾脏-矿物质和骨病(CKD-MBD)。这个概念包含了系统性疾病影响的死亡率。血管钙化是心血管疾病发展和死亡的独立危险因素。预防和治疗血管钙化的最佳策略是CKD-MBD的管理。通过对血管钙化机理的深入研究,有望在未来出现直接预防血管钙化的治疗方法。
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[The prevention and treatment of vascular calcification.]

We had called the various bone disorder in chronic kidney disease(CKD)as a "ROD:renal osteodystrophy" until last decade. However the concept of ROD have changed into the chronic kidney disease-mineral and bone disease(CKD-MBD)within this decade. This concept is containing systemic disorder affected mortality. Vascular calcification is an independent risk factor for the development of cardiovascular disease and mortality. The best strategy to prevent and treat vascular calcification would consist of the CKD-MBD management. It is expected that the treatment of preventing directly vascular calcification to appear by finding the detailed mechanism in the future.

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