卵巢癌妇女恶性腹水的处理及其对生活质量的影响。

Larissa Meyer, Rudy Suidan, Charlotte Sun, Shannon Westin, Robert L Coleman, Gordon B Mills
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引用次数: 0

摘要

恶性腹水是上皮性卵巢癌最常见的后遗症之一。它会导致严重的症状,对患者的生活质量产生不利影响,尤其是对于复发性卵巢癌患者。无症状腹水的治疗包括旨在排出腹腔积水的机械治疗和预防及减少腹水发生的药物治疗。机械疗法包括连续腹腔穿刺术、腹膜导管和腹腔静脉分流术。药物治疗包括利尿剂、血管生成抑制剂和其他靶向药物。有一种未经正式分析的观点认为,难治性腹水在紫杉类药物治疗时代并不常见。在这篇综述论文中,我们将重点介绍当前和新出现的治疗策略、并发症和禁忌症,以及它们对患者生活质量的影响。
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The management of malignant ascites and impact on quality of life outcomes in women with ovarian cancer.

Malignant ascites is one of the most common sequela of epithelial ovarian cancer. It causes significant symptoms and can have a detrimental impact on patient quality of life, especially in women with recurrent ovarian cancer. The management of symptomatic ascites consists of both mechanical treatments that aim to drain the peritoneal cavity, and medical therapies that prevent and diminish the development of ascites. Mechanical options include serial paracentesis, peritoneal catheters, and peritoneovenous shunts. Pharmaceutical treatments include diuretics, angiogenesis inhibitors, and other targeted agents. There is a perception, without formal analysis, that intractable ascites is less common in the taxane era of therapy. In this review paper, we highlight current and emerging therapeutic strategies, complications and contraindications, and their effects on patient quality of life.

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