William Craig Stagner, Shalini Gaddam, Rudrangi Parmar, Ajay Kumar Ghanta
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引用次数: 4
摘要
八乙酸蔗糖(SOA)是美国国家处方(NF)专著药典材料(美国药典，2008)，如图1所示，有八个醋酸基团连接到蔗糖部分。它是一种天然产品，从金叶番荔枝种子中提取(Lima et al.， 2011)。它是无毒的(Sigma-Aldrich, 2016)，并且基于它的苦味有许多用途。例如，当糖的浓度为0.06% (w/w) SOA时，糖会变得太苦(Mann et al.， 1992)。SOA可以形成255种不同的异构体和降解产物，它们都具有非常低的摩尔吸收率。其在210nm处的紫外摩尔吸收率在水中为439个吸收单位/cm/M，在30:70的乙腈水中为442个吸收单位/cm/M。
Sucrose octaacetate (SOA) is a United States National Formulary (NF) monograph compendial material (U.S. Pharmacopeia, 2008), and, as shown in Fig. 1, has eight acetate groups attached to a sucrose moiety. It is a natural product that has been extracted from the seeds of Annona cornifolia (Lima et al., 2011). It is nontoxic (Sigma-Aldrich, 2016) and has a number of uses based on its bitter taste. For example, sugar is rendered too bitter is eat at a concentration of 0.06% (w/w) SOA (Mann et al., 1992). SOA can form 255 different possible isomers and degradation products, all of which have a very low molar absorptivity. Its ultraviolet molar absorptivity at 210nm has been reported to be 439 absorption units/cm/M in water and 442 absorption units/cm/M in 30:70 acetonitrile-water.
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