关注西替利嗪在临床实践中的应用:30年后的重新评估。

IF 2.3 Multidisciplinary Respiratory Medicine Pub Date : 2019-12-06 eCollection Date: 2019-01-01 DOI:10.1186/s40248-019-0203-6

Angelo G Corsico, Salvatore Leonardi, Amelia Licari, Gianluigi Marseglia, Michele Miraglia Del Giudice, Diego G Peroni, Carmelo Salpietro, Giorgio Ciprandi

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引用次数: 9

摘要

抗组胺药是目前最常用的药物之一。它们用于治疗继发于组胺释放的症状，这是某些过敏性疾病的典型症状，包括鼻炎、结膜炎、哮喘、荨麻疹和过敏反应。西替利嗪属于第二代家族，因此，它对外周H1受体具有很强的选择性，有效且快速缓解症状，具有额外的抗过敏/抗炎作用，并且通常耐受性良好。它已经上市30年了。这些年来，已经建立了大量的证据。目前的综述提供了在临床实践中使用西替利嗪的实际更新。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Focus on the cetirizine use in clinical practice: a reappraisal 30 years later.

Antihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma, urticaria, and anaphylaxis. Cetirizine belongs to the second-generation family, so, it is very selective for peripheral H1 receptors, is potent and quickly relieves symptoms, exerts additional anti-allergic/anti-inflammatory effects, and is usually well-tolerated. It has been marketed 30 years ago. In these years, a remarkable body of evidence has been built. The current review provides a practical update on the use of cetirizine in clinical practice.

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来源期刊

Multidisciplinary Respiratory Medicine Medicine-Pulmonary and Respiratory Medicine

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期刊介绍： Multidisciplinary Respiratory Medicine is the official journal of the Italian Respiratory Society - Società Italiana di Pneumologia (IRS/SIP). The journal publishes on all aspects of respiratory medicine and related fields, with a particular focus on interdisciplinary and translational research. The interdisciplinary nature of the journal provides a unique opportunity for researchers, clinicians and healthcare professionals across specialties to collaborate and exchange information. The journal provides a high visibility platform for the publication and dissemination of top quality original scientific articles, reviews and important position papers documenting clinical and experimental advances.