经筛选的输血献血者血液中疟原虫的发病率。

Q2 Medicine Malaria Research and Treatment Pub Date : 2019-11-25 eCollection Date: 2019-01-01 DOI:10.1155/2019/1457406
Samuel Antwi-Baffour, Ransford Kyeremeh, Atta Poku Amoako, Lawrence Annison, John Ocquaye-Mensah Tetteh, Mahmood Abdulai Seidu
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引用次数: 9

摘要

疟疾是一种由疟原虫属五种中的一种或多种引起的人类原生动物寄生虫感染,其负担在世界各地,特别是在热带地区是众所周知的。另一方面,输血是挽救生命的必要干预措施。然而,如果血液是由感染者捐献的,则可能导致输血传播感染,包括疟疾。因此,在疟疾易发环境中对献血者的血液进行彻底的疟疾寄生虫检查是很重要的。本研究的目的是调查献血者血液中疟原虫的发生率。使用显微镜、快速诊断测试(RDT)和疟疾寄生虫分子方法对来自捐助者的总共1500个样本进行了检查。分别用显微镜法、RDT法和分子法在48份、49份和47份血样中检出疟原虫。平均患病率为3.2%。除O型和A型阴性血外,所有血型均有疟疾阳性。所有阳性标本均检出恶性疟原虫滋养体。血型和疟疾寄生虫的流行之间没有关联。年龄与疟疾寄生虫流行率之间也没有关联。结果证明输血传播疟疾的潜在风险,从而对接受血液的人,特别是疟疾易感人群儿童和孕妇构成巨大风险。尽管本研究的流行率还不够高,再加上其他地方的其他结果,可以说,对捐献的血液或献血者进行疟疾寄生虫筛查是必要的,以便采取措施,不向有风险的患者输血。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The Incidence of Malaria Parasites in Screened Donor Blood for Transfusion.

Malaria is a protozoan parasitic infection of humans resulting from one or more of the five species of the genus Plasmodium and its burden across the world particularly in the tropics is well known. Blood transfusion on the other hand is a necessary intervention in saving lives. However, it can lead to transfusion transmitted infections including malaria if the blood was donated by an infected person. It is therefore important that the blood from donors in malaria prone environment be examined thoroughly for malaria parasites. The objective of this study was to investigate the incidence of malaria parasites in donor blood. A total of 1,500 samples from donors were examined using microscopy, rapid diagnostic test (RDT), and molecular method for malaria parasites. Malaria parasites were detected in forty-eight (48), 49 and 47 of the blood samples using microscopy, RDT, and molecular method respectively. This gave an average prevalence of 3.2%. All the blood groups examined had some malaria positivity except blood group O and A negative. In all the positive samples, the trophozoites of Plasmodium falciparum were detected. There was no association between blood group type and prevalence of the malaria parasites. There was also no association between age and prevalence of malaria parasite. The results attest to the potential risk of blood transfusion transmitted malaria and thus pose a great risk to blood recipients, especially the malaria vulnerable groups of children and pregnant women. Even though the prevalence in this study was not high enough, together with other results from elsewhere, it can be said that the screening of donated blood or donors for malaria parasites is necessary so that measures will be put in place not to transfuse patients at risk.

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来源期刊
Malaria Research and Treatment
Malaria Research and Treatment Medicine-Infectious Diseases
CiteScore
5.20
自引率
0.00%
发文量
0
期刊介绍: Malaria Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to all aspects of malaria.
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