瑞克斯团队委员会提交的2017年EUPA YPIC

Q4 Biochemistry, Genetics and Molecular Biology EuPA Open Proteomics Pub Date : 2019-03-01 DOI:10.1016/j.euprot.2019.07.009

Lindsay K. Pino, Brian C Searle, Han-Yin Yang

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摘要

主要使用LC-MS/MS de novo测序技术，我们得出结论，这些肽形成了JJ汤姆森爵士在《正电射线及其在化学分析中的应用》的序言中的以下句子:“我确信，化学中有许多问题可以用这种方法比用任何其他方法更容易解决。这种方法非常灵敏，甚至比光谱分析还要灵敏，只需要极少量的材料，而且不需要特别纯化。”在这里，我们详细介绍了我们的过程，破译肽混合物的组成，并找到他们形成的句子和句子来自哪本书。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Team COUNCIL OF RICKS submission for EUPA YPIC 2017

Using primarily LC-MS/MS de novo sequencing techniques, we concluded that the peptides form the following sentence from Sir JJ Thomson’s preface to Rays of Positive Electricity and Their Application to Chemical Analyses:

“I feel sure that there are many problems in chemistry which could be solved with far greater ease by this than by any other method. The method is surprisingly sensitive, more so even than that of spectrum analysis, requires an infinitesimal amount of material, and does not require this to be specially purified.”

Here, we detail our process for deciphering the peptide mixture composition and finding the sentence they form and from what book the sentence comes from.

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