农药(农用化学品)毒理学评价用犬一年重复剂量口服毒性研究综述(农药专家委员会决定,FSCJ,2017年12月21日)。

Food safety (Tokyo, Japan) Pub Date : 2018-12-21 eCollection Date: 2018-12-01 DOI:10.14252/foodsafetyfscj.2018008s
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引用次数: 1

摘要

在农药(农用化学品)的毒理学评估中,已根据对啮齿动物(如大鼠和小鼠)以及非啮齿动物(如兔子和狗)的研究对其毒性进行了评估。在此,根据日本食品安全委员会(FSCJ)对农药毒性研究1)、国际趋势和科学观点进行的研究,重新考虑了犬慢性毒性研究用于农药毒理学评估的必要性。
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Review on the One-year Repeated Dose Oral Toxicity Study in Dogs for the Toxicological Evaluation of Pesticides (Agricultural Chemicals) (Decision of the Expert Committee on Pesticide, FSCJ, 21 December 2017).

In the toxicological evaluation of pesticides (agricultural chemicals), their toxicities have been evaluated based on studies in rodents such as rats and mice as well as in non-rodents such as rabbits and dogs. Here, reflecting a research performed under the Food Safety Commission of Japan (FSCJ) grant on pesticide toxicity study1), international trends and also scientific points of view, the necessity of chronic dog toxicity studies was reconsidered for the use in toxicological evaluation of pesticides.

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