阿齐沙坦酯钾。

Q1 Pharmacology, Toxicology and Pharmaceutics Profiles of drug substances, excipients, and related methodology Pub Date : 2020-01-01 Epub Date: 2019-12-06 DOI:10.1016/bs.podrm.2019.10.001
Abdulrahman A Al-Majed, Ahmed H H Bakheit, Ali Al-Muhsin, Hamad M Al-Kahtani, Ali S Abdelhameed
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引用次数: 0

摘要

阿兹沙坦用于治疗高血压。降低高血压可以避免中风、心脏病发作和肾脏问题。阿兹沙坦被命名为血管紧张素受体阻滞剂(ARBs)作为一类药物。它的作用是放松血管,使血液更容易流动。阿兹沙坦美多索米是一个全面的介绍,包括描述,配方,元素分析,用途和应用。此外,还概述了该原料药的制备方法和方案。研究了药物的物理性质,包括电离常数、溶解度、x射线粉末衍射图、差示扫描量热、热传导和光谱研究。原料药和/或制剂中用于分析原料药的方法包括分光光度法、电化学法和色谱法。对该原料药的稳定性、药物应用、作用机制、药效学和给药信息等方面的研究进行了综述。在本概要的最后,列出了60多个参考文献。
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Azilsartan medoxomil.

Azilsartan is used for treatment of the high blood pressure (hypertension). Reducing high blood pressure enables avoid strokes, heart attacks and problems of kidneys. Azilsartan comes under the name angiotensin receptor blocker (ARBs) as a class of drugs. It acts by relaxing blood vessels to make it easier for blood to flow. Azilsartan Medoxomil's a comprehensive profile containing the description, formulae, Elemental Analysis, Uses and application. Furthermore, methods and schemes are outlined for the preparation of the drug substance. The physical properties of the medication include constant of ionization, solubility, X-ray powder diffraction pattern, differential scanning calorimetry, thermal conduct and spectroscopic studies are investigated. The methods employed in bulk medicines and/or in pharmaceutical formulations to analyze the drug substance include spectrophotometric, electrochemical and the chromatographic methods. Other studies on this drug substance include drug stability, Pharmaceutical Applications, Mechanism of Action, Pharmacodynamics, and a Dosing Information are reviewed. At the end of this profile, there are more than sixty references were listed.

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来源期刊
Profiles of drug substances, excipients, and related methodology
Profiles of drug substances, excipients, and related methodology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
13.10
自引率
0.00%
发文量
4
期刊最新文献
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