干细胞在神经再生中的应用。

Brain and neuroscience advances Pub Date : 2018-12-05 eCollection Date: 2018-01-01 DOI:10.1177/2398212818818071
Kirsty Goncalves, Stefan Przyborski
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引用次数: 5

摘要

干细胞在生物医学研究中的应用是一个非常活跃的科学领域。这是因为它们提供的工具既可以在体内使用,也可以在体外使用,以替代在退行性过程中丢失的细胞,或者对这类疾病进行建模,以阐明其潜在机制。这篇综述旨在讨论干细胞在神经系统内提供再生方面的应用,这在中枢神经系统的神经元缺乏固有的再生和修复失去的连接的能力时尤为重要。随着人口老龄化,神经退行性疾病的发病率正在增加,这突出表明需要更好地了解再生能力和干细胞在这一领域的许多用途。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The utility of stem cells for neural regeneration.

The use of stem cells in biomedical research is an extremely active area of science. This is because they provide tools that can be used both in vivo and vitro to either replace cells lost in degenerative processes, or to model such diseases to elucidate their underlying mechanisms. This review aims to discuss the use of stem cells in terms of providing regeneration within the nervous system, which is particularly important as neurons of the central nervous system lack the ability to inherently regenerate and repair lost connections. As populations are ageing, incidence of neurodegenerative diseases are increasing, highlighting the need to better understand the regenerative capacity and many uses of stem cells in this field.

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