盘尾丝虫病动态:模拟治疗、教育和病媒控制的效果。

IF 1.8 4区 数学 Q3 ECOLOGY Journal of Biological Dynamics Pub Date : 2020-12-01 DOI:10.1080/17513758.2020.1745306
Asha Hassan, Nyimvua Shaban
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引用次数: 5

摘要

考虑了盘尾丝虫病动态的确定性模型,该模型基于疾病状态将社区划分为隔间。在使用伊维菌素药物进行大规模治疗期间,在社区提供公共卫生教育。对病媒种群实施杀幼虫和诱捕策略,控制黑蝇种群的增长。我们将模型与数据拟合以检验模型的适用性。推导了这些策略对繁殖数影响的表达式。数值结果表明,当四种策略同时实施时,盘尾丝虫病的动态和黑蝇的生长得到了最好的控制。研究结果还表明,为了在社会上彻底消灭这种疾病,有必要寻找一种替代伊维菌素,既能杀死成虫,又能应用于不符合条件的人的药物。
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Onchocerciasis dynamics: modelling the effects of treatment, education and vector control.

A deterministic model of onchocerciasis disease dynamics is considered in a community partitioned into compartments based on the disease status. Public health education is offered in the community during the implementation of mass treatment using ivermectin drugs. Also, larviciding and trapping strategies are implemented in the vector population with the aim of controlling population growth of black flies. We fit the model to the data to check the suitability of the model. Expressions are derived for the influence on the reproduction numbers of these strategies. Numerical results show that the dynamics of onchocerciasis and the growth of black flies are best controlled when the four strategies are implemented simultaneously. Also, the results suggest that for the elimination of the disease in the society there is a need for finding another drug which will be implemented to ineligible human as well as killing the adult worms instead of ivermectin.

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来源期刊
Journal of Biological Dynamics
Journal of Biological Dynamics ECOLOGY-MATHEMATICAL & COMPUTATIONAL BIOLOGY
CiteScore
4.90
自引率
3.60%
发文量
28
审稿时长
33 weeks
期刊介绍: Journal of Biological Dynamics, an open access journal, publishes state of the art papers dealing with the analysis of dynamic models that arise from biological processes. The Journal focuses on dynamic phenomena at scales ranging from the level of individual organisms to that of populations, communities, and ecosystems in the fields of ecology and evolutionary biology, population dynamics, epidemiology, immunology, neuroscience, environmental science, and animal behavior. Papers in other areas are acceptable at the editors’ discretion. In addition to papers that analyze original mathematical models and develop new theories and analytic methods, the Journal welcomes papers that connect mathematical modeling and analysis to experimental and observational data. The Journal also publishes short notes, expository and review articles, book reviews and a section on open problems.
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