马氏克鲁维菌合成酯酶能力的研究。

IF 1.2 Q2 Biochemistry, Genetics and Molecular Biology Journal of Molecular Microbiology and Biotechnology Pub Date : 2019-01-01 Epub Date: 2020-04-23 DOI:10.1159/000507551
Francisco Javier Reyes-Sánchez, Jesús Bernardo Páez-Lerma, Juan Antonio Rojas-Contreras, Javier López-Miranda, Nicolás Óscar Soto-Cruz, Manuel Reinhart-Kirchmayr
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引用次数: 12

摘要

最近,在非酵母菌中发现了生物技术的机会,因为它们具有导致产生感兴趣的化合物的代谢特性。研究表明,马氏克鲁维菌在生产具有重要工业意义的芳香族化合物酯方面具有很大的潜力。控制酯合成的遗传碱基包括一大群酶,其中最重要的是醇乙酰转移酶(aatase)和酯酶(aeatase),已知其中一些存在于K. marxianus中,因为它具有与酿酒酵母相似的遗传特征。由于它是生长速度最快的真核微生物,并且相对于其他酵母具有广泛的耐热性,因此它也具有适合生物技术使用的生理特性。本文基于NCBI数据库中报道的序列,分析了K. marxianus参与酯类合成的酶学背景。
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Study of the Enzymatic Capacity of Kluyveromyces marxianus for the Synthesis of Esters.

Recently, biotechnological opportunities have been found in non-Saccharomyces yeasts because they possess metabolic characteristics that lead to the production of compounds of interest. It has been observed that Kluyveromyces marxianus has a great potential in the production of esters, which are aromatic compounds of industrial importance. The genetic bases that govern the synthesis of esters include a large group of enzymes, among which the most important are alcohol acetyl transferases (AATases) and esterases (AEATases), and it is known that some are present in K. marxianus, because it has genetic characteristics like S. cerevisiae. It also has a physiology suitable for biotechnological use since it is the eukaryotic microorganism with the fastest growth rate and has a wide range of thermotolerance with respect to other yeasts. In this work, the enzymatic background of K. marxianus involved in the synthesis of esters is analyzed, based on the sequences reported in the NCBI database.

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来源期刊
Journal of Molecular Microbiology and Biotechnology
Journal of Molecular Microbiology and Biotechnology 生物-生物工程与应用微生物
CiteScore
3.90
自引率
0.00%
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0
审稿时长
>12 weeks
期刊介绍: We are entering a new and exciting era of microbiological study and application. Recent advances in the now established disciplines of genomics, proteomics and bioinformatics, together with extensive cooperation between academic and industrial concerns have brought about an integration of basic and applied microbiology as never before.
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