生活在贝鲁特的黎巴嫩儿童尿液中铝的生物监测。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2020-05-04 DOI:10.12659/MSMBR.922414
Rania El-Majzoub
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引用次数: 0

摘要

铝(Al)是一种无处不在的有毒金属,婴幼儿极易受到伤害。高铝暴露与各种人类疾病有关。本生物监测(BM)研究的目的是为贝鲁特7个月至4岁儿童的尿铝(Al)水平提供背景。材料与方法我们使用配备电热雾化的岛津原子吸收分光光度计-6300系统和GFA-EX7i石墨炉收集并分析了120份尿液标本。结果尿中Al的均值和标准差为8.978±12.275 μg/L,均在德国、台湾和波兰人群的较低范围内。维生素摄入量、大米粉和使用铝器皿被证明是尿中铝水平的主要决定因素(显著性为95%)。结论岛津原子吸收分光光度计-6300系统再次被证明是测定尿中铝水平的最佳、可靠的仪器,特别是在使用GFA-EX7i热解石墨炉时。在黎巴嫩儿童的尿液中发现了高水平的铝。然而,经常食用罐头食品并不是决定尿液中铝含量的重要因素。
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Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut.

BACKGROUND Aluminum (Al) is a ubiquitous, toxic metal to which infants and young toddlers are highly vulnerable. High Al exposure has been associated with various human pathologies. The aim of the present biomonitoring (BM) study was to provide a background for the levels of urinary aluminum (Al) in children ages 7 months to 4 years living in Beirut. MATERIAL AND METHODS We collected and analyzed 120 urine specimens using the Shimadzu Atomic Absorption Spectrophotometer-6300 system equipped with an electrothermal atomization, and using a GFA-EX7i graphite furnace. RESULTS The mean and standard deviation of Al level in urine revealed 8.978±12.275 μg/L, which is within the lower range of each of populations in Germany, Taiwan, and Poland. Vitamin intake, powder rice, and the use of Al utensils proved to be major determinants for Al level in urine (significant at 95%). CONCLUSIONS The Shimadzu Atomic Absorption Spectrophotometer-6300 system proved again to be an optimal and reliable instrument that can be used for the determination of Al level in urine, especially if using a GFA-EX7i pyrolytic graphite furnace. High levels of Al were found in the urine of Lebanese children. However, the frequent consumption of canned food did not prove to be a significant factor in determining the Al level in urine.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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