土耳其弓形虫病的来源和血清流行率。

3区 医学 Q1 Immunology and Microbiology Advances in Parasitology Pub Date : 2020-01-01 Epub Date: 2020-02-10 DOI:10.1016/bs.apar.2020.01.021
Aysegul Taylan-Ozkan
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引用次数: 0

摘要

在土耳其,人类弓形虫病被认为是一种罕见疾病,这种疾病没有具体症状,这可能是临床医生低估和诊断不足的主要原因。尽管国内有几项关于内脏幼虫迁徙的血清流行病学研究,但由于血清学检测没有标准化,因此很难对它们进行比较。在市场上引入易于获得的ELISA试剂盒后,血清流行病学研究的数量有所增加,其中报告的比率在1%至56%之间。与其他国家类似,土耳其弓形虫血清阳性在男性、儿童、生活在农村地区、收入水平较低、养狗、咬指甲或食土者中更为常见。此外,弓形虫病是兽医、农民和宠物店工作人员的一个危险因素。在呼吸、神经精神、肌肉骨骼、皮肤和腹部疾病中,弓形虫的血清阳性率明显较高。也有许多研究表明嗜酸性粒细胞在弓形虫病中的重要性。总之,尽管土耳其对弓形虫病进行了许多研究,但仍不清楚感染在多大程度上导致了过多的症状。诊断方法的标准化和分子技术的使用可以进一步阐明真实的流行病学和感染在诱发体征和症状中的作用。
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Sources and seroprevalence of toxocariasis in Turkey.

Toxocariasis in humans is considered a rare disease in Turkey, and the absence of specific symptoms of this disease is probably the main reason for clinicians to underestimate and underdiagnose the disease. Although there are several seroepidemiological studies on visceral larva migrans in the country, a comparison between them is difficult as the serological tests are not standardised. After the introduction of the easily accessible ELISA kit in the market, the number of seroepidemiological studies has increased in which the reported rates ranged between 1% and 56%. Similar to other countries, Toxocara seropositivity in Turkey is more common in men, childhood, in those living in rural area, having a low income level, owning dogs, and biting their nails or practicing geophagia. In addition, toxocariasis is a risk factor for veterinarians, farmers, and pet-shop workers. Toxocara seroprevalence is significantly higher in respiratory, neuropsychiatric, musculoskeletal, skin and abdominal disorders. There are also many studies showing the importance of eosinophilia in toxocariasis. In conclusion, although there are many studies on toxocariasis in Turkey, it is still not well understood to what extent the infection is responsible for a plethora ascribed symptoms. Standardisation of the diagnostic methods and the use of molecular techniques could further throw light in the real epidemiology and the role played by the infection to induce signs and symptoms.

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来源期刊
Advances in Parasitology
Advances in Parasitology 医学-寄生虫学
CiteScore
9.00
自引率
0.00%
发文量
28
审稿时长
>12 weeks
期刊介绍: Advances in Parasitology is recognised as a leading review serial which is consistently well placed in terms of impact factor and citations. Major reviews on all aspects of medical, veterinary and wild-life parasitology are considered. The journal provides an outlet for authoritative reviews from experts in the field. While emphasis is given to modern molecular approaches contributions across all disciplines are encouraged including traditional areas such as ecology and taxonomy. Eclectic volumes are supplemented by thematic volumes dedicated to a particular topic of recognised interest and importance.
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