{"title":"粒子治疗:质子和重离子。","authors":"Alexandra D Jensen","doi":"10.1159/000457929","DOIUrl":null,"url":null,"abstract":"<p><p>Particle therapy is a comparatively new radiotherapy treatment form allowing the application of extremely conformal treatment plans. In head and neck malignancies, especially in the paranasal sinus and anterior skull base, this technology is very valuable in order to maintain normal tissue tolerance of critical structures while still applying high doses to the tumour. The following paper will further explore the rationale of particle therapy and available clinical experience of the most commonly treated malignancies arising in these anatomical sites. The potential of particle therapy for re-irradiation in tumours of the paranasal sinus and anterior skull base will also be summarised.</p>","PeriodicalId":39848,"journal":{"name":"Advances in Oto-Rhino-Laryngology","volume":"84 ","pages":"87-105"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Particle Therapy: Protons and Heavy Ions.\",\"authors\":\"Alexandra D Jensen\",\"doi\":\"10.1159/000457929\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Particle therapy is a comparatively new radiotherapy treatment form allowing the application of extremely conformal treatment plans. In head and neck malignancies, especially in the paranasal sinus and anterior skull base, this technology is very valuable in order to maintain normal tissue tolerance of critical structures while still applying high doses to the tumour. The following paper will further explore the rationale of particle therapy and available clinical experience of the most commonly treated malignancies arising in these anatomical sites. The potential of particle therapy for re-irradiation in tumours of the paranasal sinus and anterior skull base will also be summarised.</p>\",\"PeriodicalId\":39848,\"journal\":{\"name\":\"Advances in Oto-Rhino-Laryngology\",\"volume\":\"84 \",\"pages\":\"87-105\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Oto-Rhino-Laryngology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000457929\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/7/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Oto-Rhino-Laryngology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000457929","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/7/30 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Particle therapy is a comparatively new radiotherapy treatment form allowing the application of extremely conformal treatment plans. In head and neck malignancies, especially in the paranasal sinus and anterior skull base, this technology is very valuable in order to maintain normal tissue tolerance of critical structures while still applying high doses to the tumour. The following paper will further explore the rationale of particle therapy and available clinical experience of the most commonly treated malignancies arising in these anatomical sites. The potential of particle therapy for re-irradiation in tumours of the paranasal sinus and anterior skull base will also be summarised.
期刊介绍:
Material for each volume in this series has been skillfully selected to document the most active areas of otorhinolaryngology and related specialties, such as neuro-otology and oncology. The series reproduces results from basic research and clinical studies pertaining to the pathophysiology, diagnosis, clinical symptoms, course, prognosis and therapy of a variety of ear, nose and throat disorders. The numerous papers correlating basic research findings and clinical applications are of immense value to all specialists engaged in the ongoing efforts to improve management of these disorders. Acting as a voice for its field, the series has also been instrumental in developing subspecialities into established specialities.