真核生物中运动蛋白及运动蛋白相关蛋白的功能。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2020-12-01 DOI:10.1080/19336918.2020.1810939
Iftikhar Ali, Wei-Cai Yang
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引用次数: 28

摘要

运动蛋白是ATP驱动的微管运动酶的一个超家族,它将ATP水解的化学能转化为微管轨道上的机械能。运动蛋白存在于所有真核生物中,对所有真核细胞都是必不可少的,参与多种细胞功能,如微管动力学和形态发生,染色体分离,纺锤体形成和伸长以及细胞器的运输。在这篇综述中,我们探讨了最近报道的真核生物中运动蛋白的功能,并比较了它们在植物和动物领域的具体货物,以了解基于它们在其他领域的报道功能的未知马达在一个领域的可能作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The functions of kinesin and kinesin-related proteins in eukaryotes.

Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic cells, involved in diverse cellular functions such as microtubule dynamics and morphogenesis, chromosome segregation, spindle formation and elongation and transport of organelles. In this review, we explore recently reported functions of kinesins in eukaryotes and compare their specific cargoes in both plant and animal kingdoms to understand the possible roles of uncharacterized motors in a kingdom based on their reported functions in other kingdoms.

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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
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