{"title":"免疫活性寄主眼眶感染的研究。","authors":"Mingkwan Lumyongsatien, Pimkwan Jaru-Ampornpan, Mongkol Uiprasertkul, Dinesh Selva","doi":"10.1155/2020/8827074","DOIUrl":null,"url":null,"abstract":"<p><p>Orbital mucormycosis caused by <i>Saksenaea vasiformis</i> is extremely rare. Herein, we report an immunocompetent 22-year-old Thai female who presented with two months of progressive right upper eyelid mass, associated with swelling, redness, and ptosis. She failed to improve despite multiple courses of antibiotic and steroid treatment. Computed tomography (CT) scan showed infiltration involving the upper eyelid and lacrimal gland. Fungal hyphae were revealed by histopathological study. Polymerase chain reaction (PCR) was positive for <i>Saksenaea vasiformis</i> (GenBank: accession number FR687327.1). The patient was successfully treated with surgical debridement, amphotericin B, and oral posaconazole.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2020 ","pages":"8827074"},"PeriodicalIF":0.7000,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/8827074","citationCount":"2","resultStr":"{\"title\":\"Orbital Infection by Saksenaea vasiformis in an Immunocompetent Host.\",\"authors\":\"Mingkwan Lumyongsatien, Pimkwan Jaru-Ampornpan, Mongkol Uiprasertkul, Dinesh Selva\",\"doi\":\"10.1155/2020/8827074\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Orbital mucormycosis caused by <i>Saksenaea vasiformis</i> is extremely rare. Herein, we report an immunocompetent 22-year-old Thai female who presented with two months of progressive right upper eyelid mass, associated with swelling, redness, and ptosis. She failed to improve despite multiple courses of antibiotic and steroid treatment. Computed tomography (CT) scan showed infiltration involving the upper eyelid and lacrimal gland. Fungal hyphae were revealed by histopathological study. Polymerase chain reaction (PCR) was positive for <i>Saksenaea vasiformis</i> (GenBank: accession number FR687327.1). The patient was successfully treated with surgical debridement, amphotericin B, and oral posaconazole.</p>\",\"PeriodicalId\":9603,\"journal\":{\"name\":\"Case Reports in Ophthalmological Medicine\",\"volume\":\"2020 \",\"pages\":\"8827074\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2020-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1155/2020/8827074\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Ophthalmological Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2020/8827074\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Ophthalmological Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2020/8827074","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 2
摘要
眼窝毛霉病是一种极为罕见的眼窝毛霉病。在此，我们报告了一位22岁的泰国女性，她表现出两个月的进行性右上眼睑肿块，伴有肿胀、发红和上睑下垂。尽管进行了多次抗生素和类固醇治疗，她的病情仍未好转。计算机断层扫描(CT)显示浸润累及上眼睑和泪腺。组织病理学检查显示真菌菌丝。聚合酶链反应(PCR)检测结果为阳性(GenBank: accession number FR687327.1)。患者经手术清创、两性霉素B和口服泊沙康唑治疗成功。
Orbital Infection by Saksenaea vasiformis in an Immunocompetent Host.
Orbital mucormycosis caused by Saksenaea vasiformis is extremely rare. Herein, we report an immunocompetent 22-year-old Thai female who presented with two months of progressive right upper eyelid mass, associated with swelling, redness, and ptosis. She failed to improve despite multiple courses of antibiotic and steroid treatment. Computed tomography (CT) scan showed infiltration involving the upper eyelid and lacrimal gland. Fungal hyphae were revealed by histopathological study. Polymerase chain reaction (PCR) was positive for Saksenaea vasiformis (GenBank: accession number FR687327.1). The patient was successfully treated with surgical debridement, amphotericin B, and oral posaconazole.
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