来自世界中部的光化角化病,厄瓜多尔。

Q2 Medicine BMC Dermatology Pub Date : 2020-10-27 DOI:10.1186/s12895-020-00109-8
Martha Fors, Paloma González, Carmen Viada, Kirsten Falcón, Santiago Palacios
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引用次数: 3

摘要

背景:厄瓜多尔首都基多因其地理位置,皮肤癌发病率较高。光化性角化病,作为恶性前病变,是非黑色素瘤皮肤癌的前兆,这种疾病在国内的患病率尚不清楚。方法:进行一项观察性横断面研究,以评估基多农村地区光化性角化病(AKs)的患病率。目视皮肤检查、皮肤镜检查和可疑病变活检。结果:共入组254名年龄在40岁以上的受试者(71.3%为女性)。AK总患病率为22.4%;在女性中,患病率为23.6%,在男性中,患病率为19.4%。基底细胞癌、鳞状细胞癌和Bowen病的患病率分别为1.6%、0.8%和0.4%。AKs与研究变量之间未发现统计学关联。结论:本研究首次报道了厄瓜多尔癌前病变的患病率。我们无法证明ak的存在与任何已知的发展风险因素之间的关系。
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Actinic keratoses in subjects from la Mitad del Mundo, Ecuador.

Background: Quito, the capital of Ecuador due to its geographical location, has a high skin cancer incidence. Actinic keratoses, as premalignant lesions, are precursors of nonmelanoma skin cancer, and the prevalence of this medical condition in the country is unknown.

Methods: An observational, cross-sectional study was performed to assess the prevalence of actinic keratoses (AKs) in a rural area of Quito. Visual skin exams, dermoscopy and biopsy of suspicious lesions were performed.

Results: A total of 254 subjects older than 40 years old (71.3% female) were enrolled. The general AK prevalence was 22.4%; in women, the prevalence was 23.6%, while in men, it was 19.4%. The prevalence rates of basocellular and squamous cell carcinomas and Bowen disease were 1.6, 0.8 and 0.4%, respectively. No statistical associations were found between AKs and the studied variables.

Conclusions: This study was the first reporting the prevalence of premalignant lesions in Ecuador. We could not demonstrate a relationship between the presence of AKs and any of the known risk factors for their development.

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BMC Dermatology
BMC Dermatology Medicine-Dermatology
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期刊介绍: BMC Dermatology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of skin disorders, as well as related molecular genetics, pathophysiology, and epidemiology. BMC Dermatology (ISSN 1471-5945) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus and Google Scholar.
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