Ru（ii）催化的二茂铁与溴炔烃的C–H炔化反应，由羧酰胺基团指导†

Organic chemistry frontiers : an international journal of organic chemistry Pub Date : 2023-01-01 DOI:10.1039/d3qo00069a

Ru-Yuan Zhao , Jing Zhang , Rui-Han Niu , Jin-Heng Li , Bo Sun

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引用次数: 0

摘要

在弱配位酰胺基团的影响下，通过Ru（ii）催化的与容易获得的溴炔烃化合物的直接选择性C–H单炔化，有效地合成了二茂铁衍生物。该方案提供了一种使用羧酰胺用容易转化的炔烃制备各种二茂铁衍生物的方法，得到高达89%产率的炔基化二茂铁。

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Ru(ii)-catalyzed C–H alkynylation of ferrocenes with bromoalkynes directed by carboxamide groups†

An efficient synthesis of ferrocene derivatives via Ru(ii)-catalyzed direct selective C–H mono-alkynylation with easily accessible bromoalkyne compounds under the influence of weakly coordinating amide groups has been presented. This protocol provides an approach for accessing various ferrocene derivatives with easily transformed alkynes using carboxamides, giving alkynylated ferrocenes in up to 89% yield.

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来源期刊

Organic chemistry frontiers : an international journal of organic chemistry

CiteScore

7.80

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0.00%

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