Shenglin Zhang , Xin Gao , Dongxia Wang , Yinong Jiang , Yan Liu
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引用次数: 2
摘要
醛固酮影响心肌纤维化和重构。目的是探讨高血压患者血浆醛固酮浓度(PAC)与左心房(LA)功能的关系。对148例高血压患者进行了研究。通过应变和应变率成像评价LA相函数。根据PAC分为两组，II组LA舒张早期应变和应变率(LAS-E和LASR-E)低于I组(P <0.05)。多因素回归分析显示，LAS-E与PAC独立相关(β = - 0.581, P <0.001)。总之，高血压患者PAC与左室导管功能有关。
Association between elevated plasma aldosterone concentration and left atrial conduit function in hypertension
Aldosterone affects myocardial fibrosis and remodeling. The aim was to investigate the relationship between plasma aldosterone concentration (PAC) and left atrial (LA) function in hypertension. 148 hypertensive patients were studied. LA phasic function was evaluated by strain and strain rate imaging. Patients were divided into two groups based on PAC. LA early diastolic strain and strain rate (LAS-E and LASR-E) were lower in group II compared with group I (P < 0.05). Multivariate regression analysis showed that LAS-E was independently related to PAC (β = −0.581, P < 0.001). In conclusion, PAC is associated with LA conduit function in hypertension.
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