为什么我们需要血清学检测来诊断严重急性呼吸综合征冠状病毒2 ?

Q2 Biochemistry, Genetics and Molecular Biology BioResearch Open Access Pub Date : 2020-12-02 eCollection Date: 2020-01-01 DOI:10.1089/biores.2020.0026
Bouchra Ghazi, Adil Elghanmi
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引用次数: 0

摘要

考虑到COVID-19正在出现并迅速演变的情况,与死亡率和感染风险水平上升有关,以快速、安全和准确的措施发现和确定新的检测方法将对及时做出临床和流行病学管理决策产生重大影响。实时聚合酶链反应与免疫球蛋白m类免疫球蛋白G类抗体血清学检测相结合,可以成为更准确诊断严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)感染的有力策略,减少错误结果的出现。以下观点描述了对SARS-Cov-2感染的免疫反应及其在选择适当诊断工具中的意义。
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Why Do We Need Serological Tests for Severe Acute Respiratory Syndrome Coronavirus-2 Diagnosis?

Considering the COVID-19 emerging and rapidly evolving situation associated with increased levels of mortality and infectivity risks, the detection and identification of new tests in a fast, safe, and accurate measures would have a high impact regarding prompt clinical and epidemiological management decisions. The combination of real-time polymerase chain reaction and the immunoglobulin class M-immunoglobulin class G antibody serology testing can be a powerful strategy for more accurate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosis with less false results slipping through the cracks. The following viewpoint is describing the immunological response to SARS-Cov-2 infection and its implication in the selection of the appropriate diagnosis tools.

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来源期刊
BioResearch Open Access
BioResearch Open Access Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
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期刊介绍: BioResearch Open Access is a high-quality open access journal providing peer-reviewed research on a broad range of scientific topics, including molecular and cellular biology, tissue engineering, regenerative medicine, stem cells, gene therapy, systems biology, genetics, virology, and neuroscience. The Journal publishes basic science and translational research in the form of original research articles, comprehensive review articles, mini-reviews, rapid communications, brief reports, technology reports, hypothesis articles, perspectives, and letters to the editor.
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