Jiarui Li, Fang Hua, Peng Xu, Cui Huang, Hongye Yang
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引用次数: 2
摘要
目的:系统地回顾体外研究，评估在添加或不添加脱敏剂的情况下粘接剂-牙本质结合强度。材料和方法:在四个数据库(PubMed, Embase, Web of Science和Cochrane Library)中进行检索，根据系统评价首选报告项目(PRISMA)，没有出版日期或语言限制。两名审稿人选择研究，提取数据，并独立评估偏倚风险。纳入标准是评价在粘接步骤中使用脱敏剂后立即或老化粘接强度的影响。偏倚风险按照Sarkis-Onofre等人使用的方法进行评估。41使用Review Manager 5.3进行meta分析。结果:采用上述检索策略共检索到1636篇文章;选择59篇文章进行全文分析，对32篇进行系统综述，其中18篇纳入meta分析。结果表明，不同种类的脱敏剂之间存在显著差异。亚组比较显示不同种类的脱敏剂具有高度的异质性。酪蛋白磷酸肽-无定形磷酸钙(CPP-ACP)和精氨酸- caco3的使用对直接结合强度没有负面影响，而其他脱敏剂对直接结合强度有一定影响。结论:不同的脱敏剂对微拉伸粘结强度有不同的影响。脱敏剂可根据结合强度选择，特别用于牙齿准备后缓解牙齿敏感。
Effects of Desensitizers on Adhesive-Dentin Bond Strength: A Systematic Review and Meta-analysis.
Purpose: To systematically review in vitro studies that evaluated adhesive-dentin bond strength with or without the addition of desensitizers.
Materials and methods: A search was conducted in four databases (PubMed, Embase, Web of Science, and Cochrane Library) without publication date or language limits in accordance with the Preferred Reporting Items for Systematic Reviews (PRISMA). Two reviewers selected the studies, extracted data, and assessed the risk of bias independently. The inclusion criterion was the evaluation of the effect of immediate or aged bond strength after applying desensitizer in the bonding step. The risk of bias was assessed following the method used by Sarkis-Onofre et al.41 Meta-analysis was conducted using Review Manager 5.3.
Results: A total of 1636 articles were found using the search strategy above; 59 articles were selected for full-text analysis, and 32 were systematically reviewed, with 18 considered in the meta-analysis. Results showed a significant difference among various kinds of desensitizers. The subgroup comparison showed high heterogeneity among the different kinds of desensitizers. The use of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and arginine-CaCO3 showed no negative effect on the immediate bond strength, whereas other desensitizers showed some influence.
Conclusion: Different desensitizers have various effects on microtensile bond strength. Desensitizers may be selected based on the bond strength and especially used to relieve tooth sensitivity after tooth preparation.
期刊介绍：
New materials and applications for adhesion are profoundly changing the way dentistry is delivered. Bonding techniques, which have long been restricted to the tooth hard tissues, enamel, and dentin, have obvious applications in operative and preventive dentistry, as well as in esthetic and pediatric dentistry, prosthodontics, and orthodontics. The current development of adhesive techniques for soft tissues and slow-releasing agents will expand applications to include periodontics and oral surgery. Scientifically sound, peer-reviewed articles explore the latest innovations in these emerging fields.
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