{"title":"不同义齿清洁剂用量对白色念珠菌抗菌活性的影响。","authors":"Cha-Hwan Bae, Yun-Kyong Lim, Joong-Ki Kook, Mee-Kyoung Son, Yu-Ri Heo","doi":"10.4047/jap.2021.13.2.100","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against <i>Candida albicans</i>.</p><p><strong>Materials and methods: </strong>This study used tablet-type denture cleansers, Polident®, Coolingdent® and Fittydent®, along with liquid denture cleansers, Hexamedine®, Listerine® and Apple vinegar®. The antibacterial activities of denture cleansers were evaluated based on the number of <i>C. albicans</i> and concentrations of the denture cleansers.</p><p><strong>Results: </strong>In the 0.5 × 10<sup>6</sup> cfu/ml culture medium, the <i>C. albicans</i>' death rate of Polident® was significantly lower than those of Fittydent®, Hexamedine®, Listerine®, and Apple vinegar®(<i>P</i><.05). In the 0.5 × 10<sup>7</sup> cfu/, the <i>C. albicans</i>' death rates of Polident® and Coolingdent® were significantly lower than those of Fittydent®, Hexamedine®, Listerine® and Apple vinegar®(<i>P</i><.05). The <i>C. albicans</i>' death rates of Polident® and Coolingdent® were significantly decreased at 0.02 g and 0.01 g. The <i>C. albicans</i>' death rate of Fittydent® was significantly decreased at 0.005 g (<i>P</i><.05). The <i><i>C. albicans</i></i> ' death rate of Hexamedine® was significantly decreased at 1/16 dilution. The <i>C. albicans</i>' death rate of Listerine® was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegar® was decreased at 1/4 dilution (<i>P</i><.05).</p><p><strong>Conclusion: </strong>As the number of <i>C. albicans</i> increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% <i>C. albicans</i>' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.</p>","PeriodicalId":51291,"journal":{"name":"Journal of Advanced Prosthodontics","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/23/jap-13-100.PMC8110740.pdf","citationCount":"4","resultStr":"{\"title\":\"Evaluation of antibacterial activity against <i>Candida albicans</i> according to the dosage of various denture cleansers.\",\"authors\":\"Cha-Hwan Bae, Yun-Kyong Lim, Joong-Ki Kook, Mee-Kyoung Son, Yu-Ri Heo\",\"doi\":\"10.4047/jap.2021.13.2.100\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against <i>Candida albicans</i>.</p><p><strong>Materials and methods: </strong>This study used tablet-type denture cleansers, Polident®, Coolingdent® and Fittydent®, along with liquid denture cleansers, Hexamedine®, Listerine® and Apple vinegar®. The antibacterial activities of denture cleansers were evaluated based on the number of <i>C. albicans</i> and concentrations of the denture cleansers.</p><p><strong>Results: </strong>In the 0.5 × 10<sup>6</sup> cfu/ml culture medium, the <i>C. albicans</i>' death rate of Polident® was significantly lower than those of Fittydent®, Hexamedine®, Listerine®, and Apple vinegar®(<i>P</i><.05). In the 0.5 × 10<sup>7</sup> cfu/, the <i>C. albicans</i>' death rates of Polident® and Coolingdent® were significantly lower than those of Fittydent®, Hexamedine®, Listerine® and Apple vinegar®(<i>P</i><.05). The <i>C. albicans</i>' death rates of Polident® and Coolingdent® were significantly decreased at 0.02 g and 0.01 g. The <i>C. albicans</i>' death rate of Fittydent® was significantly decreased at 0.005 g (<i>P</i><.05). The <i><i>C. albicans</i></i> ' death rate of Hexamedine® was significantly decreased at 1/16 dilution. The <i>C. albicans</i>' death rate of Listerine® was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegar® was decreased at 1/4 dilution (<i>P</i><.05).</p><p><strong>Conclusion: </strong>As the number of <i>C. albicans</i> increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% <i>C. albicans</i>' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.</p>\",\"PeriodicalId\":51291,\"journal\":{\"name\":\"Journal of Advanced Prosthodontics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2021-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/23/jap-13-100.PMC8110740.pdf\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Advanced Prosthodontics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4047/jap.2021.13.2.100\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/4/27 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Prosthodontics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4047/jap.2021.13.2.100","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/4/27 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 4
摘要
目的:本研究的目的是比较目前购买的义齿清洁剂对白色念珠菌的抗菌活性。材料和方法:本研究使用片剂型义齿清洁剂Polident®、Coolingdent®和Fittydent®,以及液体义齿清洁剂hexedine®、Listerine®和苹果醋®。根据白色念珠菌的数量和假牙清洁剂的浓度来评价假牙清洁剂的抗菌活性。结果:在0.5 × 106 cfu/ml培养基中,Polident®的白色念珠菌死亡率显著低于Fittydent®、己甲定®、李斯特林®和苹果醋®(P7 cfu/), Polident®和Coolingdent®的白色念珠菌死亡率显著低于Fittydent®、己甲定®、李斯特林®和苹果醋®(PC)。0.02 g和0.01 g时,Polident®和Coolingdent®的白念珠菌死亡率显著降低。0.005 g (PC)显著降低Fittydent®的白色念珠菌死亡率。稀释1/16时,己塞定®的白色念珠菌死亡率显著降低。稀释1/8时,李斯特林®的白色念珠菌死亡率降低,稀释1/4时,苹果醋®的抗菌活性降低(p结论:随着白色念珠菌数量的增加,义齿清洁剂的抗菌活性降低。在片剂型义齿清洁剂中,使用1片剂量时,所有义齿清洁剂的白色念珠菌死亡率均为100%。一种义齿清洁剂仅用1/3片就显示出同样的抗菌效果。在液体型义齿清洁剂中,每种义齿清洁剂所需的稀释程度不同。
Evaluation of antibacterial activity against Candida albicans according to the dosage of various denture cleansers.
Purpose: The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against Candida albicans.
Materials and methods: This study used tablet-type denture cleansers, Polident®, Coolingdent® and Fittydent®, along with liquid denture cleansers, Hexamedine®, Listerine® and Apple vinegar®. The antibacterial activities of denture cleansers were evaluated based on the number of C. albicans and concentrations of the denture cleansers.
Results: In the 0.5 × 106 cfu/ml culture medium, the C. albicans' death rate of Polident® was significantly lower than those of Fittydent®, Hexamedine®, Listerine®, and Apple vinegar®(P<.05). In the 0.5 × 107 cfu/, the C. albicans' death rates of Polident® and Coolingdent® were significantly lower than those of Fittydent®, Hexamedine®, Listerine® and Apple vinegar®(P<.05). The C. albicans' death rates of Polident® and Coolingdent® were significantly decreased at 0.02 g and 0.01 g. The C. albicans' death rate of Fittydent® was significantly decreased at 0.005 g (P<.05). The C. albicans ' death rate of Hexamedine® was significantly decreased at 1/16 dilution. The C. albicans' death rate of Listerine® was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegar® was decreased at 1/4 dilution (P<.05).
Conclusion: As the number of C. albicans increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% C. albicans' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.
期刊介绍:
This journal aims to convey scientific and clinical progress in the field of prosthodontics and its related areas to many dental communities concerned with esthetic and functional restorations, occlusion, implants, prostheses, and biomaterials related to prosthodontics.
This journal publishes
• Original research data of high scientific merit in the field of diagnosis, function, esthetics and stomatognathic physiology related to prosthodontic rehabilitation, physiology and mechanics of occlusion, mechanical and biologic aspects of prosthodontic materials including dental implants.
• Review articles by experts on controversies and new developments in prosthodontics.
• Case reports if they provide or document new fundamental knowledge.