{"title":"近期与抗衰老有关的一些论文评论:2021年6月。","authors":"Benjamin Zealley, Aubrey D N J de Grey","doi":"10.1089/rej.2021.0028","DOIUrl":null,"url":null,"abstract":"<p><p>Theses reviewed in this issue include \"Engineering Protein Disaggregases to Counter Alpha-Synuclein and Amyloid-Beta Neurotoxicity,\" \"Hyperglycaemia Induced Immunomodulation of Macrophages in Diabetic Vascular Disease,\" \"Microvasculature-on-a-Chip Systems for Human Disease Modeling,\" \"Senescence Surveillance: The Interplay Between the Immune System and Senescent Cells,\" \"The HMG Transcription Factor TOX Induces a Transcriptional and Epigenetic Program of CD8<sup>+</sup> T Cell Exhaustion in Chronic Infection and Cancer,\" and \"Zero to One-Translational Advancements in the Field of Xenotransplantation.\"</p>","PeriodicalId":20979,"journal":{"name":"Rejuvenation research","volume":"24 3","pages":"238-243"},"PeriodicalIF":2.2000,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Commentary on Some Recent Theses Relevant to Combating Aging: June 2021.\",\"authors\":\"Benjamin Zealley, Aubrey D N J de Grey\",\"doi\":\"10.1089/rej.2021.0028\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Theses reviewed in this issue include \\\"Engineering Protein Disaggregases to Counter Alpha-Synuclein and Amyloid-Beta Neurotoxicity,\\\" \\\"Hyperglycaemia Induced Immunomodulation of Macrophages in Diabetic Vascular Disease,\\\" \\\"Microvasculature-on-a-Chip Systems for Human Disease Modeling,\\\" \\\"Senescence Surveillance: The Interplay Between the Immune System and Senescent Cells,\\\" \\\"The HMG Transcription Factor TOX Induces a Transcriptional and Epigenetic Program of CD8<sup>+</sup> T Cell Exhaustion in Chronic Infection and Cancer,\\\" and \\\"Zero to One-Translational Advancements in the Field of Xenotransplantation.\\\"</p>\",\"PeriodicalId\":20979,\"journal\":{\"name\":\"Rejuvenation research\",\"volume\":\"24 3\",\"pages\":\"238-243\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2021-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rejuvenation research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1089/rej.2021.0028\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"GERIATRICS & GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rejuvenation research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/rej.2021.0028","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
Commentary on Some Recent Theses Relevant to Combating Aging: June 2021.
Theses reviewed in this issue include "Engineering Protein Disaggregases to Counter Alpha-Synuclein and Amyloid-Beta Neurotoxicity," "Hyperglycaemia Induced Immunomodulation of Macrophages in Diabetic Vascular Disease," "Microvasculature-on-a-Chip Systems for Human Disease Modeling," "Senescence Surveillance: The Interplay Between the Immune System and Senescent Cells," "The HMG Transcription Factor TOX Induces a Transcriptional and Epigenetic Program of CD8+ T Cell Exhaustion in Chronic Infection and Cancer," and "Zero to One-Translational Advancements in the Field of Xenotransplantation."
期刊介绍:
Rejuvenation Research publishes cutting-edge, peer-reviewed research on rejuvenation therapies in the laboratory and the clinic. The Journal focuses on key explorations and advances that may ultimately contribute to slowing or reversing the aging process, and covers topics such as cardiovascular aging, DNA damage and repair, cloning, and cell immortalization and senescence.
Rejuvenation Research coverage includes:
Cell immortalization and senescence
Pluripotent stem cells
DNA damage/repair
Gene targeting, gene therapy, and genomics
Growth factors and nutrient supply/sensing
Immunosenescence
Comparative biology of aging
Tissue engineering
Late-life pathologies (cardiovascular, neurodegenerative and others)
Public policy and social context.