Muhammet Aydin, Elif Burcu Aydin, Mustafa Kemal Sezgintürk
{"title":"免疫传感器技术的进展。","authors":"Muhammet Aydin, Elif Burcu Aydin, Mustafa Kemal Sezgintürk","doi":"10.1016/bs.acc.2020.08.001","DOIUrl":null,"url":null,"abstract":"<p><p>In recent years, advances in immunosensor device fabrication have significantly expanded the use of this technology in a broad range of applications including clinical diagnosis, food analysis, quality control, environmental studies and industrial monitoring. The most important aspect in fabrication is to obtain a design that provides a low detection limit. The utilization of nanomaterials as a label, catalyst and biosensing transducer is, perhaps, the most popular approach in ultrasensitive devices. This chapter reviews recent advances in immunosensor fabrication and summarizes the most recent studies. Strategies employed to significantly improve sensitivity and specificity of immunosensor technology and the advantages and limitations thereof are explored.</p>","PeriodicalId":50872,"journal":{"name":"Advances in Clinical Chemistry","volume":"102 ","pages":"1-62"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.acc.2020.08.001","citationCount":"20","resultStr":"{\"title\":\"Advances in immunosensor technology.\",\"authors\":\"Muhammet Aydin, Elif Burcu Aydin, Mustafa Kemal Sezgintürk\",\"doi\":\"10.1016/bs.acc.2020.08.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In recent years, advances in immunosensor device fabrication have significantly expanded the use of this technology in a broad range of applications including clinical diagnosis, food analysis, quality control, environmental studies and industrial monitoring. The most important aspect in fabrication is to obtain a design that provides a low detection limit. The utilization of nanomaterials as a label, catalyst and biosensing transducer is, perhaps, the most popular approach in ultrasensitive devices. This chapter reviews recent advances in immunosensor fabrication and summarizes the most recent studies. Strategies employed to significantly improve sensitivity and specificity of immunosensor technology and the advantages and limitations thereof are explored.</p>\",\"PeriodicalId\":50872,\"journal\":{\"name\":\"Advances in Clinical Chemistry\",\"volume\":\"102 \",\"pages\":\"1-62\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/bs.acc.2020.08.001\",\"citationCount\":\"20\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Clinical Chemistry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/bs.acc.2020.08.001\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/9/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"Chemistry\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Clinical Chemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/bs.acc.2020.08.001","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/9/14 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"Chemistry","Score":null,"Total":0}
In recent years, advances in immunosensor device fabrication have significantly expanded the use of this technology in a broad range of applications including clinical diagnosis, food analysis, quality control, environmental studies and industrial monitoring. The most important aspect in fabrication is to obtain a design that provides a low detection limit. The utilization of nanomaterials as a label, catalyst and biosensing transducer is, perhaps, the most popular approach in ultrasensitive devices. This chapter reviews recent advances in immunosensor fabrication and summarizes the most recent studies. Strategies employed to significantly improve sensitivity and specificity of immunosensor technology and the advantages and limitations thereof are explored.
期刊介绍:
Advances in Clinical Chemistry volumes contain material by leading experts in academia and clinical laboratory science. The reviews cover a wide variety of clinical chemistry disciplines including clinical biomarker exploration, cutting edge microarray technology, proteomics and genomics. It is an indispensable resource and practical guide for practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general.