为帕金森病患者提供锻炼的合作方法--PDConnect 计划的可行性和可接受性研究[第 2 版;同行评审:2 人通过]。

Julie Jones, Lyndsay Alexander, Elizabeth Hancock, Kay Cooper
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摘要

背景:运动已被证明对帕金森病患者(PwP)有益,可减缓运动症状和非运动症状的衰退速度,新的证据表明运动具有神经保护作用。目前所提供的运动是有时间限制的,而且缺乏支持长期坚持运动的策略。随着帕金森病患者的不断增加,有必要制定长期可持续的运动方法。本研究的主要目的是评估旨在促进帕金森病患者体育锻炼和自我管理的多成分干预(PDConnect)的可行性和可接受性:方法:将开展一项收敛固定平行混合方法设计研究。研究旨在招募 30 名残疾人,并将他们随机分配到两组:(i) 常规护理组将接受每周一次的物理治疗,为期六周,通过 Microsoft Teams 进行。(ii) PDConnect 组将接受每周一次的物理治疗,为期六周,由英国国家医疗服务体系的帕金森病专业物理治疗师通过 Microsoft Teams 提供运动、教育和行为改变干预。随后,接受过帕金森病专门培训的健身教练将通过 Microsoft Teams 每周进行 12 次团体锻炼。然后,健身教练将在三个月内每月通过视频会议与参与者联系一次,以支持他们参与锻炼。研究期间将收集主要可行性数据,并在研究结束时通过半结构化访谈评估接受度。次要结果包括运动、非运动以及健康和幸福指数,将在基线、6 周、18 周和 30 周时进行评估:这项试点研究将确定 PDConnect 是否可行,是否能为残疾人所接受。这将为更大规模的评估提供一个平台,以评估 PDConnect 在提高帕金森病患者运动参与度和自我管理方面的有效性:已在 ISRCTN 上注册(ISRCTN11672329,2020 年 6 月 4 日)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A collaborative approach to exercise provision for people with Parkinson's - a feasibility and acceptability study of the PDConnect programme [version 2; peer review: 2 approved].

Background: Exercise has been shown to be beneficial for people with Parkinson's (PwP), slowing the rate of decline of motor and nonmotor symptoms, with emerging evidence associating exercise with a neuroprotective effect. Current exercise provision is time-limited, and delivered in the absence of strategies to support long-term adherence to exercise. With a growing Parkinson's population, there is a need to develop long-term sustainable approaches to exercise delivery. The primary aim of this study is to assess the feasibility and acceptability of a multicomponent intervention (PDConnect) aimed at promoting physical activity, and self-management for PwP.

Methods: A convergent fixed parallel mixed methods design study will be undertaken. The study aims to recruit 30 PwP, who will be randomly allocated into two groups: (i) the usual care group will receive physiotherapy once a week for six weeks delivered via Microsoft Teams. (ii) The PDConnect group will receive physiotherapy once a week for six weeks which combines exercise, education and behaviour change interventions delivered by NHS Parkinson's specialist physiotherapists via Microsoft Teams. This will be followed by 12 weekly sessions of group exercise delivered on Microsoft Teams by fitness instructors specially trained in Parkinson's. Participants will be then contacted by the fitness instructors once per month for three months by video conferencing to support exercise engagement. Primary feasibility data will be collected during the study, with acceptability assessed via semi-structured interviews at the end. Secondary outcomes encompassing motor, non-motor and health and well-being measures will be assessed at baseline, at six, 18, and 30 weeks.

Discussion: This pilot study will establish whether PDConnect is feasible and acceptable to PwP. This will provide a platform for a larger evaluation to assess the effectiveness of PDConnect at increasing exercise participation and self-management within the Parkinson's Community.

Trial registration: Registered on ISRCTN (ISRCTN11672329, 4th June 2020).

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