【从放射治疗室释放的131I-MIBG患者的辐射防护】。

Anri Inaki, Hiroshi Wakabayashi, Daiki Kayano, Seigo Kinuya
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引用次数: 0

摘要

131I-3-碘苄基胍或131I-iobenguane (3-(131I)碘苄基胍或131I-iobenguane [131I- mibg])是一种放射性物质,在嗜铬细胞瘤和神经母细胞瘤等肿瘤细胞中特异性积累。由于131I释放的细胞毒性射线,它已被开发为放射性同位素治疗的药物,一些研究人员已经报道了它的有效性。在本研究中,我们根据以往131I-MIBG治疗临床试验的患者数据,评估了接受131I-MIBG治疗的患者放射的辐射对公众暴露的辐射安全性。结果认为,来访者和护理人员对患者的公共暴露和医疗暴露符合现行的131 - 1治疗后患者释放标准,低于其剂量限值和剂量约束。
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[Radiation Protection Against Exposure from Patients Receiving 131I-MIBG and Released from Radiation Treatment Room].

131I-3-iodobenzylguanidine or 131I-iobenguane (3-(131I) iodobenzylguanidine or 131I-iobenguane [131I-MIBG]) is a radioactive agent that is specifically accumulated in tumor cells such as pheochromocytoma and neuroblastoma. Due to its cytotoxic beta ray emitted from 131I, it has been developed as an agent for radioisotope therapy and some researchers have reported its effectiveness. In this study, based on the patients' data from previous clinical trials of 131I-MIBG therapy, we evaluated the radiation safety for public exposure caused by radiation emitted from patients who received 131I-MIBG. In results, it was considered that public exposure and medical exposure of visitors and caregivers to the patients were less than their dose limit and dose constraint by complying the current criteria of the release of patients after therapy with 131I.

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期刊介绍: The main scope of JSNM is the appropriate development of the application of radioactive substances and stable nuclides in medicine. Towards this scope, JSNM promotes the exchange of idea and information, and researches in nuclear medicine. JSNM are interested in the international collaboration for the development of nuclear medicine. Through the activities, JSNM contributes to the medicine, as well as humanity, not only in Japan but also in any countries over the world.
期刊最新文献
[The 44th Report on Survey of the Adverse Reaction to Radiopharmaceuticals (The 47th Survey in 2021)].
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