G Tetè, B D'orto, L Ferrante, E Polizzi, F Cattoni
{"title":"肥大细胞在口腔炎症中的作用。","authors":"G Tetè, B D'orto, L Ferrante, E Polizzi, F Cattoni","doi":"10.23812/21-4supp1-6","DOIUrl":null,"url":null,"abstract":"<p><p>Mast cells play important roles in the maintenance of many physiological functions as well as in the pathophysiology of diseases. Mast cells are involved in the inflammatory mechanisms of many systemic diseases. In this pandemic period, their role in physiological and pathological host inflammatory reactions in tissue disruption following SARS-CoV-2 infection has been stressed. A review of the literature was carried out by entering the key words \"Mast Cells\" AND \"Oral Diseases\" AND \"Role of Mast Cells in Periodontitis\". The results show us that mast cells are definitely involved in many oral diseases including periodontitis. Further in vivo and in vitro studies are needed to further investigate the specific role of the cells in physiological and pathological inflammation.</p>","PeriodicalId":15084,"journal":{"name":"Journal of biological regulators and homeostatic agents","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"15","resultStr":"{\"title\":\"Role of mast cells in oral inflammation.\",\"authors\":\"G Tetè, B D'orto, L Ferrante, E Polizzi, F Cattoni\",\"doi\":\"10.23812/21-4supp1-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Mast cells play important roles in the maintenance of many physiological functions as well as in the pathophysiology of diseases. Mast cells are involved in the inflammatory mechanisms of many systemic diseases. In this pandemic period, their role in physiological and pathological host inflammatory reactions in tissue disruption following SARS-CoV-2 infection has been stressed. A review of the literature was carried out by entering the key words \\\"Mast Cells\\\" AND \\\"Oral Diseases\\\" AND \\\"Role of Mast Cells in Periodontitis\\\". The results show us that mast cells are definitely involved in many oral diseases including periodontitis. Further in vivo and in vitro studies are needed to further investigate the specific role of the cells in physiological and pathological inflammation.</p>\",\"PeriodicalId\":15084,\"journal\":{\"name\":\"Journal of biological regulators and homeostatic agents\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2021-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"15\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biological regulators and homeostatic agents\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.23812/21-4supp1-6\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biological regulators and homeostatic agents","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.23812/21-4supp1-6","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Mast cells play important roles in the maintenance of many physiological functions as well as in the pathophysiology of diseases. Mast cells are involved in the inflammatory mechanisms of many systemic diseases. In this pandemic period, their role in physiological and pathological host inflammatory reactions in tissue disruption following SARS-CoV-2 infection has been stressed. A review of the literature was carried out by entering the key words "Mast Cells" AND "Oral Diseases" AND "Role of Mast Cells in Periodontitis". The results show us that mast cells are definitely involved in many oral diseases including periodontitis. Further in vivo and in vitro studies are needed to further investigate the specific role of the cells in physiological and pathological inflammation.
期刊介绍：
Journal of Biological Regulators & Homeostatic Agents (IF 1.397) is a peer-reviewed journal published every 2 months. The journal publishes original papers describing research in the fields of experimental and clinical medicine, molecular biology, biochemistry, regulatory molecules, cellular immunology and pharmacology.
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