甲状腺软骨骨软骨瘤1例报告及文献复习。

IF 0.4 Q4 OTORHINOLARYNGOLOGY Case Reports in Otolaryngology Pub Date : 2021-09-02 eCollection Date: 2021-01-01 DOI:10.1155/2021/8286012
Jessa E Miller, Shaghauyegh S Azar, Dinesh K Chhetri
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摘要

骨软骨瘤是一种较为常见的良性骨肿瘤,常位于长骨干骺端;然而,他们是罕见的头颈部区域。本研究的目的是提出一个由甲状腺软骨引起的骨软骨瘤的病例,并进行文献回顾。方法:回顾性分析1例甲状软骨骨软骨瘤的临床资料。使用PubMed和Google Scholar对骨软骨瘤进行文献检索。本文综述了骨软骨瘤的流行病学、表现、诊断、治疗和预后。结果:一名50岁的女性表现为九个月的发音障碍和语音中断。喉部频闪镜检查显示左假声带丰满、声门间隙及振动相位不对称。颈部CT显示左侧甲状腺软骨层有一个边界清晰的5 × 8 × 9 mm肿块,边缘呈薄钙化,中心呈非均匀性衰减。手术切除了肿瘤。组织病理学分析显示透明软骨覆盖板层骨并伴有脂肪性骨髓,符合骨软骨瘤。英文文献复习未发现甲状软骨骨软骨瘤病例。骨软骨瘤的表现可能取决于病变的大小和位置。鉴别骨肿瘤的良恶性是至关重要的,医生必须依靠临床检查、影像学表现和组织病理学分析来做出正确的诊断。结论:喉架骨软骨瘤极为罕见,据我们所知,尚无文献报道这种肿瘤起源于甲状腺软骨。发音障碍可能是甲状腺软骨肿块患者的主要症状,引起真声带活动受限。
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Osteochondroma Arising from the Thyroid Cartilage: A Case Report and Literature Review.

Introduction: Osteochondromas are relatively common benign bone tumors often located at the metaphyseal ends of long bones; however, they are rare in the head and neck region. The objective of this study is to present a case of an osteochondroma arising from the thyroid cartilage causing insidious dysphonia and to present a literature review.

Methods: The medical record of a patient treated for osteochondroma of the thyroid cartilage was reviewed. A literature search on osteochondromas was conducted using PubMed and Google Scholar. The epidemiology, presentation, diagnosis, treatment, and outcomes of osteochondromas were reviewed.

Results: A 50-year-old female presented with nine months of dysphonia and aphonic voice breaks. Laryngovideostroboscopy revealed a left false vocal fold fullness, glottal gap, and vibratory phase asymmetry. A CT neck demonstrated a well-circumscribed 5 × 8 × 9 mm mass arising from the left thyroid cartilage lamina with a thin calcified rim and a heterogeneous decreased attenuation center. The tumor was excised surgically. Histopathologic analysis demonstrated hyaline cartilage overlying lamellar bone with fatty bone marrow, consistent with osteochondroma. English language literature review revealed no cases of osteochondroma of the thyroid cartilage. The presenting features of osteochondroma may depend on the size and location of the lesion. It is critical to differentiate between benign and malignant bone tumors, and physicians must rely on their clinical examination, radiographic findings, and histopathologic analysis to make the correct diagnosis.

Conclusions: Osteochondromas of the laryngeal framework are extremely rare, and to our knowledge, there have been no reports in the literature of this tumor arising from the thyroid cartilage. Dysphonia may be the presenting symptom in a patient with a thyroid cartilage mass causing restricted mobility of the true vocal folds.

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来源期刊
Case Reports in Otolaryngology
Case Reports in Otolaryngology OTORHINOLARYNGOLOGY-
自引率
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发文量
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审稿时长
13 weeks
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